Results 121 to 130 of about 917,915 (175)

Stability of Dexamethasone during Hot-Melt Extrusion of Filaments based on Eudragit® RS, Ethyl Cellulose and Polyethylene Oxide. [PDF]

Int J Pharm X
Domsta V, Boralewski T, Ulbricht M, Schick P, Krause J, Seidlitz A.   +5 more
europepmc   +1 more source

Sweeteners Show a Plasticizing Effect on PVP K30-A Solution for the Hot-Melt Extrusion of Fixed-Dose Amorphous Curcumin-Hesperetin Solid Dispersions. [PDF]

Pharmaceutics
Wdowiak K, Tajber L, Miklaszewski A, Cielecka-Piontek J.   +3 more
europepmc   +1 more source

Preparation and Evaluation of Inhalable Microparticles with Improved Aerodynamic Performance and Dispersibility Using L-Leucine and Hot-Melt Extrusion. [PDF]

Pharmaceutics
Jeong JH, Kim JS, Choi YR, Shin DH, Kang JH, Kim DW, Park YS, Park CW.   +7 more
europepmc   +1 more source

QbD-Based Development and Evaluation of Pazopanib Hydrochloride Extrudates Prepared by Hot-Melt Extrusion Technique: In Vitro and In Vivo Evaluation. [PDF]

Pharmaceutics
Gupta A, Dahima R, Panda SK, Gupta A, Singh GD, Wani TA, Hussain A, Rathore D.   +7 more
europepmc   +1 more source

Comparing Low-Dose Carvedilol Continuous Manufacturing by Solid and Liquid Feeding in Self-Emulsifying Delivery Systems via Hot Melt EXtrusion (SEDEX). [PDF]

Pharmaceuticals (Basel)
Zupančič O, Matić J, Doğan A, Gaggero A, Khinast J, Paudel A.   +5 more
europepmc   +1 more source

Synergistic modification of hot-melt extrusion and nobiletin on the multi-scale structures, interactions, thermal properties, and in vitro digestibility of rice starch. [PDF]

Front Nutr
Zhang Z, Feng Y, Wang H, He H.
europepmc   +1 more source

Understanding the Interaction of Thermal, Rheological, and Mechanical Parameters Critical for the Processability of Polyvinyl Alcohol-Based Systems during Hot Melt Extrusion. [PDF]

Pharmaceutics
Hess F, Kipping T, Weitschies W, Krause J.   +3 more
europepmc   +1 more source

Development and in vitro Evaluation of Cannabidiol Mucoadhesive Buccal Film Formulations Using Hot-Melt Extrusion Technology. [PDF]

Med Cannabis Cannabinoids
Taha IE, ElSohly MA, Radwan MM, Omari S, Repka MA, Ashour EA.   +5 more
europepmc   +1 more source

Applications of Hot-Melt Extrusion for Drug Delivery [PDF]

Expert Opinion on Drug Delivery, 2008
In today's pharmaceutical arena, it is estimated that more than 40% of new chemical entities produced during drug discovery efforts exhibit poor solubility characteristics. However, over the last decade hot-melt extrusion (HME) has emerged as a powerful processing technology for drug delivery and has opened the door to a host of molecules previously ...
Michael A Repka, Sunil Kumar Battu, Ramesh Srirangam   +2 more
exaly   +3 more sources

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Hot-Melt Extrusion: a Roadmap for Product Development

AAPS PharmSciTech, 2021
Hot-melt extrusion has found extensive application as a feasible pharmaceutical technological option over recent years. HME applications include solubility enhancement, taste masking, and sustained drug release. As bioavailability enhancement is a hot topic of today's science, one of the main applications of HME is centered on amorphous solid ...
Marta F, Simões, Rui M A, Pinto, Sérgio, Simões   +2 more
openaire   +2 more sources