Results 71 to 80 of about 917,915 (175)

Fabricação por extrusão de dispositivos poliméricos para liberação de antibiótico visando aplicações médicas [PDF]

, 2011
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Ciência e Engenharia dos Materiais, Florianópolis, 2011O intento inicial deste trabalho fez-se na escolha de uma técnica de fabricação que ...
Zepon, Karine Modolon
core  

Hot-melt extrusion: process to novel pharmaceutical applications

, 2013
Over the last three decades industrial adaptability has allowed hot-melt extrusion (HME) to gain wide acceptance and has already established its place in the broad spectrum of manufacturing operations and pharmaceutical research development.
Mohammed Maniruzzaman (1626004)
core   +1 more source

The die swell eliminating mechanism of hot air assisted 3D printing of GF/PP and its influence on the product performance

e-Polymers
For eliminating the die swell phenomenon in 3D printing of GF/PP, a hot air assisted 3D printing method is proposed and its mechanism is studied. A two-phase flow model consisting of compressible gas and in-compressible melt is established, and the ...
Yang Ru, Xiao Jianhua, Liu YingLan, Xu ShiKang   +3 more
doaj   +1 more source

Review paper: Processing aspects of hot melt extrusion in pharmaceutical applications

, 2009
Applying extrusion technology to drug manufacturing received increasing attention in the last two decades. Extrusion technology has the potential of replacing current Pharmaceuticals manufacturing methods due to the advantages such as the elimination of ...
Wang, Peng, Xanthos, Marino, Gogos, Costas G., Liu, Huiju, Zhu, Linjie   +4 more
core  

Modeling of Residence Time Distributions of Twin-Screw Extrusion Processes Considering Various Screw Types

Pharmaceutics
Purpose: Residence time in pharmaceutical hot-melt extrusion is a crucial process parameter affecting the quality attributes of a dosage form such as content uniformity, bioavailability and toxicity.
Vincent Kimmel, Dario Zöllig, Werner Hoheisel, Judith Winck, Markus Thommes   +4 more
doaj   +1 more source

System-agnostic prediction of pharmaceutical excipient miscibility via computing-as-a-service and experimental validation

Scientific Reports
We applied computing-as-a-service to the unattended system-agnostic miscibility prediction of the pharmaceutical surfactants, Vitamin E TPGS and Tween 80, with Copovidone VA64 polymer at temperature relevant for the pharmaceutical hot melt extrusion ...
Georgios S. E. Antipas, Regina Reul, Kristin Voges, Samuel O. Kyeremateng, Nikolaos A. Ntallis, Konstantinos T. Karalis, Lukasz Miroslaw   +6 more
doaj   +1 more source

Application of Hot-Melt Extrusion in Modifying the Solubility of Lycopene

Applied Sciences
Lycopene is a potent antioxidant carotenoid with significant health-promoting properties. However, its practical application is limited by poor water solubility.
Anna Kulawik, Kamil Wdowiak, Maciej Kulawik, Natalia Rosiak, Magdalena Paczkowska-Walendowska, Judyta Cielecka-Piontek, Przemysław Zalewski   +6 more
doaj   +1 more source

INCREASED SOLUBILITY AND DISSOLUTION OF GELUCIRE® 50/13 SOLID DISPERSIONS CONTAINING CARBAMAZEPINE

Química Nova
Carbamazepine is widely used in the treatment of psychomotor epilepsy; however, its low aqueous solubility can limit therapeutic efficacy. In this study, solid dispersions were developed via hot melt extrusion to enhance the solubility of the drug and ...
Oscar G. da Silva Neto, Rodrigo M. Martins, Denilson L. Rocha, Gustavo L. F. Barbosa, Maria E. C. B. Rangel, Wladymyr J. B. de Sousa, Ana R. M. de Lima, Luis A. P. de Freitas   +7 more
doaj   +1 more source

Drug-Eluting Sutures by Hot-Melt Extrusion: Current Trends and Future Potentials. [PDF]

Materials (Basel), 2023
Khalid GM, Billa N.
europepmc   +1 more source

Hot melt extrusion – processing solid solutions?

Journal of Pharmacy and Pharmacology, 2014
Andrews, Gavin P., Jones, David S.
openaire   +3 more sources