Results 61 to 70 of about 917,915 (175)
Enhancing the bioavailability of hydrophobic drugs using hot melt extrusion [PDF]
, 2018 Many existing drugs (as well as new revelations) in the pharmaceutical industry bear a distinct disadvantage in the sense that they are not water soluble, displaying low bioavailability values and consequently a reduced invitro effect. Hot melt extrusion
Coffey, Conor +3 more
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Enhancing the oral drug delivery through hot melt extrusion techniques [PDF]
, 2022 Hot melt extrusion has been developed as a fresh technique for taste masking, in recent years. This method provides many aids as compared to traditional methods like avoiding the use of solvents, continuous manufacturing, ease to scale up, and ...
Komanduri, Neeraja
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Orodispersible films prepared by hot-melt extrusion versus solvent casting
International audienceThis study investigated the influence of solvent casting and hot-melt extrusion manufacturing methods on the physical, chemical, and functional properties of orodispersible films with the same composition and incorporating a poorly ...
Debeaufort, Frédéric +3 more
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Effect of particle size on release of solid dispersed particles during the "Dissolution" test
Разработка и регистрация лекарственных средствIntroduction. The use of the solid disperse systems method to increase the solubility of lipophilic active pharmaceutical ingredients is industrially applicable using different technologies, but the influence of particle size on the dissolution of these ...
S. A. Zolotov, A. V. Panov
doaj +1 more source
Journal of Excipients and Food Chemicals, 2022 The aim of this work was to improve the solubility of various anti-HIV APIs extruding them with polyvinyl alcohol to allow a reduction in patient drug burden. There are no previously known cases of successful use of this polymer to improve the solubility
Sergey A Zolotov +6 more
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Hot melt extrusion: An industrially feasible approach for casting orodispersible film
Asian Journal of Pharmaceutical Sciences, 2015 Over the recent few decades, many groups of formulation scientists are concentrating on rapid release dosage forms in oral cavity. Among all fast release dosage forms, orodispersible films are successful to attract pharmaceutical industry due to ease of ...
Rushiraj Jani, Dasharath Patel
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Properties of polymeric drug delivery systems prepared by hot-melt extrusion [PDF]
, 2002 textThe purpose of this research project was to investigate the physicochemical and drug release properties of polymeric drug delivery systems prepared by hot-melt extrusion containing either highly water-soluble drugs or a poorly water-soluble drug. The
Zhu, Yucun
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Hot-melt co-extrusion as manufacturing technique for multilayer oral dosage forms [PDF]
, 2014 Co-extrusion implies the simultaneous hot-melt extrusion of two or more materials through the same die, creating a multilayered extrudate. This innovative continuous production technology offers numerous advantages over traditional pharmaceutical ...
Dierickx, Lien
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Optimising Extrusion-based Pla-asa 3D Printed Drug Delivery Mesh Using Pat Tools
Chemical Engineering TransactionsIn this study, the use of extrusion-based 3D printing for the fabrication of a personalized drug delivery Polylactic acid (PLA) – Aspirin (ASA) mesh for bone tissue engineering is examined.
Yazan Odeh +5 more
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Materials Today AdvancesPredicting the processability of polymeric materials in hot-melt extrusion remains a critical challenge in continuous manufacturing due to the complex transition from powder feeding to melt flow under dynamic processing conditions.
Dan Trunov +4 more
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