Hot-Melt Extrusion-Based Dexamethasone-PLGA Implants: Physicochemical, Physicomechanical, and Surface Morphological Properties and In Vitro Release Corrected for Drug Degradation. [PDF]
Ghaffari AA +6 more
europepmc +1 more source
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa +4 more
wiley +1 more source
Stability of Dexamethasone during Hot-Melt Extrusion of Filaments based on Eudragit® RS, Ethyl Cellulose and Polyethylene Oxide. [PDF]
Domsta V +5 more
europepmc +1 more source
MXene‐Based Flexible Memory and Neuromorphic Devices
The unique two‐dimensional structure, excellent electrical conductivity, and diverse surface groups of MXenes have garnered significant attention. Coupled with their exceptional flexibility, MXene‐based devices hold immense potential for flexible memory and neuromorphic systems. This review comprehensively discusses the fundamentals of flexible devices,
Yan Li +13 more
wiley +1 more source
Comparing Low-Dose Carvedilol Continuous Manufacturing by Solid and Liquid Feeding in Self-Emulsifying Delivery Systems via Hot Melt EXtrusion (SEDEX). [PDF]
Zupančič O +5 more
europepmc +1 more source
Toward Real‐Life Applications of Fiber Lithium‐Ion Batteries
Fiber‐shaped lithium‐ion batteries require effective encapsulation to achieve long‐term stability in wearable applications. This work discusses different encapsulation strategies and technologies, and summarizes how encapsulation affects capacity retention, efficiency, and internal resistance.
Mengli Wei +4 more
wiley +1 more source
Sweeteners Show a Plasticizing Effect on PVP K30-A Solution for the Hot-Melt Extrusion of Fixed-Dose Amorphous Curcumin-Hesperetin Solid Dispersions. [PDF]
Wdowiak K +3 more
europepmc +1 more source
Single‐Particle Characterization Reveals Heterogeneous Extracellular Vesicle Fusion with Liposomes
This study used five orthogonal single‐particle techniques to compare how common mechanical methods fuse extracellular vesicles with liposomes. By quantifying fused‐particle yield, purity, and vesicle integrity, we found that freeze‐thaw and sonication generated the highest fusion but that all methods introduced membrane perturbation or damage.
Rachel R. Mizenko +6 more
wiley +1 more source
Synergistic modification of hot-melt extrusion and nobiletin on the multi-scale structures, interactions, thermal properties, and in vitro digestibility of rice starch. [PDF]
Zhang Z, Feng Y, Wang H, He H.
europepmc +1 more source
The study investigates the influence of DED‐Arc/M versus casting on the microstructure and material properties of X40CrMoV5‐1 (AISI H13) hot‐work tool steel. DED‐Arc/M yields finer microstructures, superior mechanical strength, and ductility, but slightly reduced thermal conductivity.
Ulf Ziesing +4 more
wiley +1 more source

