Results 51 to 60 of about 6,701 (248)

3D Printing of Self‐Healing Polymers by Material Extrusion: A Process‐Centric Review of Setups, Parameters, and Applications

Advanced Robotics Research, EarlyView.
This review highlights recent advances in material extrusion 3D printing of self‐healing polymers, focusing on the interplay between material chemistry, rheology, hardware customization, and process optimization. Filament‐ and ink‐based extrusion strategies, multimaterial architectures, and postprocessing approaches are discussed for applications in ...
Antonio Pavone, Gianni Stano, Gianluca Percoco   +2 more
wiley   +1 more source

Improving the Pharmaceutical Potential of Lycopene Using Hot-Melt Extrusion

Applied Sciences
Background: Lycopene is a powerful antioxidant, classified as a carotenoid. Numerous studies confirm its beneficial effects in both the prevention and treatment of various diseases. However, its therapeutic application is significantly limited due to its
Anna Kulawik, Maciej Kulawik, Natalia Rosiak, Wei Lu, Aleksandra Kryszak, Judyta Cielecka-Piontek, Przemysław Zalewski   +6 more
doaj   +1 more source

Application of hot melt extrusion to enhance the dissolution and oral bioavailability of oleanolic acid

Asian Journal of Pharmaceutical Sciences, 2017
The aim of this study was to improve the in vitro dissolution rate and oral bioavailability of oleanolic acid (OA), a water insoluble drug belonging to BCS class IV. Hot melt extrusion (HME) was applied to develop OA amorphous solid dispersions.
Nannan Gao, Mengran Guo, Qiang Fu, Zhonggui He   +3 more
doaj   +1 more source

Polymer‐Grafted Cu(II) Metal–Organic Polyhedra as Scalable, Melt‐Processable Porous Materials

Advanced Science, EarlyView.
The use of a direct synthetic route to obtain polymer‐grafted Cu(II)‐based metal–organic polyhedra gives rise to a low‐cost and scalable cage. This material combines low‐temperature melting, achieving phase changes while preserving cage integrity, and high CO2 uptake exceeding 0.6 mmol g−1.
Alba Cortés‐Martínez, Francisco Sánchez‐Férez, José A. Suárez del Pino, Sergio Royuela, Félix Zamora, Daniel Maspoch, Arnau Carné‐Sánchez   +6 more
wiley   +1 more source

A Review of Hot-Melt Extrusion: Process Technology to Pharmaceutical Products [PDF]

ISRN Pharmaceutics, 2012
Over the last three decades industrial adaptability has allowed hot-melt extrusion (HME) to gain wide acceptance and has already established its place in the broad spectrum of manufacturing operations and pharmaceutical research developments. HME has already been demonstrated as a robust, novel technique to make solid dispersions in order to provide ...
Mohammed Maniruzzaman, Joshua S. Boateng, Martin J. Snowden, Dennis Douroumis   +3 more
openaire   +3 more sources

Multi‐Scale Bionic Structure Constructs Biomass Flame‐Retardant Thermal Insulation Foam Material

Advanced Science, EarlyView.
Inspired by mussel adhesion and hierarchical brick‐and‐mortar architectures, a cellulose‐based biomimetic foam is constructed by anchoring bentonite nanosheets onto a polydopamine‐decorated cellulose nanofiber network. The resulting foam combines low thermal conductivity with intrinsic flame retardancy and full biodegradability, presenting a ...
Jianming Liao, Lijun Fan, Yunyuan Dong, Xuyu Bao, Xiaobin Chen, Qifu Zheng, Guanqing Zhang, Shen Wang, Wei Chen, Min Zhang, Shuaiming He   +10 more
wiley   +1 more source

Low temperature hot melt extrusion of polycaprolactone/polyethylene oxide/chitosan ternary blends for biocompatible implantable device development

Materials & Design
Rising demand for biomedical devices requires manufacturing approaches suitable for processing thermally-sensitive materials. Hot-melt extrusion may cause thermal degradation of polymers and bioactives.
Philbert Nshimiyimana, Declan Mary Colbert, Zeeshan Ali, Ciara Buckley   +3 more
doaj   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

3D-Printed Tablets of Nifurtimox: In Vitro and In Vivo Anti-Trypanosoma cruzi Studies

Pharmaceutics
Background/Objectives: Chagas disease is a neglected tropical disease caused by infection with the parasite Trypanosoma cruzi. Benznidazole and nifurtimox are the only approved drugs for treating this condition, but their low aqueous solubility may lead ...
Giselle R. Bedogni, Ana Luiza Lima, Idejan P. Gross, Tatiana Prata Menezes, Andre Talvani, Marcilio Cunha-Filho, Claudio J. Salomon   +6 more
doaj   +1 more source

Additive Manufacturing of High‐Performance Polymers for Extreme Environments

Advanced Science, EarlyView.
Additive manufacturing of high‐performance polymers for extreme environments is critically reviewed through an integrated chemistry‐processing‐structure‐property‐qualification framework. The review compares fused filament fabrication, selective laser sintering, and direct ink writing, linking rheology and thermal history to crystallization, defect ...
Md Tofazzal Hossain, Mohammed Intishar Nur, Md Shajedul Hoque Thakur, Indranil Dey, Md Mesbahul Maruf, Md Jahid Hasan, Suryasarathi Bose, Muhammad M. Rahman   +7 more
wiley   +1 more source