Results 41 to 50 of about 6,701 (248)

In-process rheometry as a PAT tool for hot melt extrusion [PDF]

Drug Development and Industrial Pharmacy, 2017
Real time measurement of melt rheology has been investigated as a Process Analytical Technology (PAT) to monitor hot melt extrusion of an Active Pharmaceutical Ingredient (API) in a polymer matrix. A developmental API was melt mixed with a commercial copolymer using a heated twin screw extruder at different API loadings and set temperatures.
Kelly, Adrian L., Gough, Tim, Isreb, Mohammad, Dhumal, Ravindra S., Jones, J.W., Nicholson, S., Dennis, A.B., Paradkar, Anant R   +7 more
openaire   +4 more sources

A Thermoreversible Gelation Pathway to Plant Cuticle‐Inspired Biopolymer Aerogel Monoliths Based on Network‐Spherulitic Crystal Assemblies

Advanced Materials, EarlyView.
To address functionality limitations in plant‐based and industrially compostable polymer aerogels, this work introduces bio‐inspired aerogels with broadened functionality. Inspired by functional plant tissues, lightweight biopolymer aerogels based on exclusively stereocomplex crystals are fabricated, featuring hierarchically macro‐/meso‐porous ...
Anthony V. Tuccitto, Zeineb Ben Rejeb, Rafaela Aguiar, Nello D. Sansone, Sumaiya Farzana, Isaac Ali, Jun Uk Lee, Daniel J. Davidson, Ailsa K. Edward, Chul B. Park, Patrick C. Lee   +10 more
wiley   +1 more source

Two-component feedstock based on ultra-high molecular weight polyethylene for additive manufacturing of medical products

Advanced Industrial and Engineering Polymer Research, 2021
Ultra-high molecular weight polyethylene (UHMWPE) possesses distinctive properties, but has an extremely low melt flow rate (MFR) of about zero, which makes it unsuitable for processing by standard methods for polymers.
S.V. Panin, D.G. Buslovich, Yu.V. Dontsov, L.A. Kornienko, V.O. Alexenko, S.A. Bochkareva, S.V. Shilko   +6 more
doaj   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Two‐Way Shape Memory Polymer Composite Gripper for Adaptive Robotic Applications

Advanced Materials Technologies, EarlyView.
A two‐way shape memory polymer (SMP) composite is developed with intrinsic shape‐changing capability driven solely by temperature, eliminating external actuation loads. Embedding the SMP in a low‐stiffness elastomeric matrix enabled reversible transformations during heating and cooling cycles.
Aamna Hameed, Kamran Ahmed Khan
wiley   +1 more source

Hot Melt Extrusion Technology in Taste Masking

AAPS PharmSciTech
Abstract Hot melt extrusion (HME) is a widely used method of taste masking in medication formulations, notably for bitter Active Pharmaceutical Ingredients (APIs). This continuous, solvent-free technique successfully wraps APIs within a polymer matrix, forming a barrier that considerably decreases bitterness perception.
Geetha Nayak, Usha Y. Nayak
openaire   +2 more sources

Programmable Variable‐Stiffness Multilayer Elastomer Composites With High‐Aspect‐Ratio Low‐Melting‐Point Alloy Inclusions

Advanced Materials Technologies, EarlyView.
High‐aspect‐ratio low‐melting‐point alloy inclusions are embedded within multilayer silicone laminates to create thermally programmable stiffness. Sequential activation of alloy‐rich layers produces four distinct mechanical states and reconfigures tendon‐driven actuator trajectories under the same load.
Palpolage Don Shehan Hiroshan Gunawardane, Gyan Edbert Zesiro, Hao Zhou, Gursel Alici, Mu Chiao   +4 more
wiley   +1 more source

Low‐Outgassing Liquid Metal–Silicone Composites for Multifunctional Space Applications

Advanced Materials Technologies, EarlyView.
Integrating liquid metal microdroplets into a space‐grade silicone creates a multifunctional composite while preserving its inherent flexibility and low‐outgassing behavior. The composite has 11×$\times$ higher thermal conductivity while remaining thermally stable and maintaining a total mass loss of ≤$\le$ 1% under thermal vacuum testing.
Spencer Pak, Matthew R. Jamison, Cadré J. Francis, Ravi Tutika, Stephen A. Morin, Eric J. Markvicka   +5 more
wiley   +1 more source

Functional Fibers in Soft Robotics: Advances in Material, Structural, and Systemic Tactics

Advanced Robotics Research, EarlyView.
Fiber‐form robotic systems offer a scalable pathway toward embodied intelligence in soft robotics. This review surveys functional fibers as material, structural, and systemic elements, highlighting advances in responsive materials, architectural programing, and fabrication strategies.
Joonhee Won, Jaehyun Jang, Hyeonseo Kim, Inyoung Choi, Steve Park, Seongjun Park   +5 more
wiley   +1 more source

Process monitoring and visualization solutions for hot-melt extrusion: a review [PDF]

Journal of Pharmacy and Pharmacology, 2014
Abstract Objectives Hot-melt extrusion (HME) is applied as a continuous pharmaceutical manufacturing process for the production of a variety of dosage forms and formulations. To ensure the continuity of this process, the quality of the extrudates must be assessed continuously during manufacturing. The
Saerens, Lien, Vervaet, Chris, Remon, Jean Paul, De Beer, Thomas   +3 more
openaire   +3 more sources