Results 31 to 40 of about 8,963,828 (215)

Processing Stability and the Significance of Variation in Extrusion Speeds and Temperatures on SSB® 55 Pharma Grade Shellac for Oral Drug Delivery

Journal of Manufacturing and Materials Processing, 2017
The melt-extrusion process is utilized in the pharmaceutical arena for the manufacturing of a variety of dosage forms and formulations, including solid dispersions.
Noel M. Gately, James E. Kennedy
doaj   +1 more source

Machine Learning for Process Monitoring and Control of Hot-Melt Extrusion: Current State of the Art and Future Directions

Pharmaceutics, 2021
In the last few decades, hot-melt extrusion (HME) has emerged as a rapidly growing technology in the pharmaceutical industry, due to its various advantages over other fabrication routes for drug delivery systems. After the introduction of the ‘quality by
Nimra Munir, Michael Nugent, Darren Whitaker, Marion McAfee   +3 more
doaj   +1 more source

A Niclosamide-releasing hot-melt extruded catheter prevents Staphylococcus aureus experimental biomaterial-associated infection

Scientific Reports, 2022
Biomaterial-associated infections are a major healthcare challenge as they are responsible for high disease burden in critically ill patients. In this study, we have developed drug-eluting antibacterial catheters to prevent catheter-related infections ...
Jesus Augusto Vazquez-Rodriguez, Bahaa Shaqour, Clara Guarch-Pérez, Emilia Choińska, Martijn Riool, Bart Verleije, Koen Beyers, Vivian J. A. Costantini, Wojciech Święszkowski, Sebastian A. J. Zaat, Paul Cos, Antonio Felici, Livia Ferrari   +12 more
doaj   +1 more source

Analysis of the conform process: a specific form of aluminium extrusion. [PDF]

Since the Conform process was patented 30 years ago, there have only been approximately 200 machines sold worldwide. Given that Conform competes economically with conventional extrusion and is also reported to be a more energy efficient process, it is ...
Velay, Xavier
core   +8 more sources

Novel Applications of Hot-Melt Extrusion Technology [PDF]

, 2018
Hot-melt extrusion, an adaptable technology, has established its position in a wide spectrum of manufacturing operations like amorphous solid dispersions, immediate and controlled oral formulations, implants, and taste masked products.
Bhagurkar, Ajinkya Moreshwar
core   +1 more source

Direct Powder Extrusion 3D Printing of Praziquantel to Overcome Neglected Disease Formulation Challenges in Paediatric Populations

Pharmaceutics, 2021
For the last 40 years, praziquantel has been the standard treatment for schistosomiasis, a neglected parasitic disease affecting more than 250 million people worldwide.
Janine Boniatti, Patricija Januskaite, Laís B. da Fonseca, Alessandra L. Viçosa, Fábio C. Amendoeira, Catherine Tuleu, Abdul W. Basit, Alvaro Goyanes, Maria-Inês Ré   +8 more
doaj   +1 more source

Polyvinyl alcohol extrudates for improving the dissolution of main protease and reverse-transcriptase inhibitors.

Journal of Excipients and Food Chemicals, 2022
The aim of this work was to improve the solubility of various anti-HIV APIs extruding them with polyvinyl alcohol to allow a reduction in patient drug burden. There are no previously known cases of successful use of this polymer to improve the solubility
Sergey A Zolotov, Natalia B Demina, Igor A Dain, Anna S Zolotova, Grigorii A Buzanov, Vasilii M Retivov, Alexander M Cheremisin   +6 more
doaj  

Micro-extrusion of fine ceramic latticework [PDF]

, 2008
PhDMicroextrusion freeforming of ceramic lattices from high solids ceramic pastes is a method for forming complex multi-scale hierarchical porous structures.
Chi, Xiaopeng
core   +4 more sources

The Effect of Hot-Melt Extrusion of Mulberry Leaf on the Number of Active Compounds and Antioxidant Activity

Plants, 2022
The aim of this study is to compare the functions of the physiologically active compounds of three types of mulberry leaf by cultivar, and to confirm the changes using hot-melt extrusion (HME−ML).
Hyun-Bok Kim, Suji Ryu, Jong-Suep Baek
doaj   +1 more source

Rational Design of Multicomponent Polymeric Systems Based on a Transient Plasticization Window for Hot-Melt Extrusion

Pharmaceutics
Background: Hot-melt extrusion (HME) is a promising technology for the manufacturing of drug products; however, its application is limited by elevated thermal and shear stresses that may induce degradation of thermolabile active pharmaceutical ...
Mark Mandrik, Veronika Makarova, Ludmila Korol, Ivan Krasnyuk, Sergey Antonov   +4 more
doaj   +1 more source