Results 241 to 250 of about 8,192,878 (290)
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Structure of the Rat's Behaviour in the Hot Plate Test
Behavioural Brain Research, 1993The objectives of the study were: (i) to elaborate an ethogram of the rat's behaviour during the hot plate test, (ii) to analyse the rat's responses to the nociceptive heat stimulus by using ethological techniques, and (iii) to discern the suitable pattern or patterns to evaluate the rat's reaction to the noxious stimulus.
Emilio F. Espejo
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The Increasing-Temperature Hot-Plate Test: An Improved Test of Nociception in Mice and Rats
Journal of Pharmacological Methods, 1991The increasing-temperature hot-plate test has several advantages compared to the conventional hot-plate test, but available equipment has been impractical and restricted with regard to stimulus control. We now describe an apparatus consisting of an aluminum plate that is heated and cooled by Peltier elements in contact with its lower surface.
Kjell Jorgen Hole +2 more
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Sweating Guarded Hot Plate Test Method
Polymer Testing, 2006 The sweating guarded hot plate instrument, simulating the heat and moisture transfer from the body surface through clothing material to the environment, was designed for the measurement of thermal resistance and water vapor permeability of fabrics, relating to comfort characteristics of the garment.
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New Hot Plate Tests to Quantify Antinociceptive and Narcotic Antagonist Activities
European Journal of Pharmacology, 1974Abstract The effects of narcotic, narcotic antagonist and non-narcotic analgetics on the responses of mice placed on hot plates at different temperatures have been investigated. In a 50°C hot plate test, the antinociceptive activities of narcotic, narcotic antagonist and non-narcotic analgetics are easily identified and quantified.
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Models of Nociception: Hot‐Plate, Tail‐Flick, and Formalin Tests in Rodents
Current Protocols in Neuroscience, 1999AbstractExperimental models of pain include tests of response thesholds to high intensity stimuli (acute pain tests) and changes in spontaneous or evoked behavioral responses in animals with peripheral injury or inflammation (persistent pain models).
Anthony W, Bannon, Annika B, Malmberg
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Antinociceptive activity of beta-adrenoceptor agonists in the hot plate test in mice
Psychopharmacology, 1986Clenbuterol, isoproterenol and salbutamol increased the latency in the licking response of mice on the hot plate at 56.5 degrees C. This effect was dose-related and obtained after IP administration. Clenbuterol was active at lower doses than isoproterenol and salbutamol, a result which is consistent with its better penetration in the central nervous ...
D, Brochet +3 more
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Effect of gender on antinociceptive effect of paroxetine in hot plate test in mice
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2006Many studies have reported both a gender difference in the rates of depression and its treatment by using any of the widely used antidepressant drug groups. Some studies suggest that females respond more poorly to tricyclic antidepressants than males and appear to respond better to selective serotonin reuptake inhibitors (SSRI).
Erdem N, Duman +5 more
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The Evaluation of Activation Energies through the Hot Plate Test
Propellants, Explosives, Pyrotechnics, 1998The hot plate test is commonly used to determine first order activation energies for energetic material. It is demonstrated that the results of this test depend significantly on the conductivity of the hot plate. Furthermore, it is demonstrated that the interface between the hot plate and the energetic material also plays a significant role in the ...
P. R. Underhill, M. F. Bardon
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Studies of tolerance development to morphine analgesia in rats tested on the hot plate
European Journal of Pharmacology, 1969Abstract Tolerance to the analgesic effect of morphine was studied in rats using the hot plate method. Animals were tested at intervals of 6 hours, 24 hours, 7 days, or 14 days after the same dose of morphine (5 mg/kg s.c.). The degree of single-dose tolerance, measured as the per cent loss of analgesic effect between the first and second tests, was ...
R K, Ferguson, W J, Adams, C L, Mitchell
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Models of Pain: Hot‐Plate and Formalin Test in Rodents
Current Protocols in Pharmacology, 1998AbstractExperimental models of pain can be separated into three basic categories: acute, persistent, and neuropathic. Acute pain is modeled by the hot‐plate test, persistent pain by the formalin test, and neuropathic pain by nerve ligation. The neurotransmitters and neuromodulators that mediate the pain response in each of these models can differ. As a
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