Results 71 to 80 of about 718,142 (310)

Macrophage polarization impacts tunneling nanotube formation and intercellular organelle trafficking. [PDF]

, 2019
Tunneling nanotubes (TNTs) are cellular extensions enabling cytosol-to-cytosol intercellular interaction between numerous cell types including macrophages.
Cherqui, Stephanie, Goodman, Spencer, Khan, Meisha, Naphade, Swati, Sharma, Jay   +4 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

MARKERS OF INCREASED RISK OF SUDDEN CARDIAC DEATH IN PATIENTS WITH STABLE ANGINA AND ARTERIAL HYPERTENSION: ASSOCIATION WITH THE PROGRESSION OF LEFT VENTRICULAR HYPERTROPHY

Российский кардиологический журнал, 2012
Aim. To analyse the markers of sudden cardiac death (SCD) in patients with stable angina and arterial hypertension (AH), in regard to the progression of left ventricular hypertrophy (LVH). Material and methods. In total, 90 patients with Functional Class
M. V. Surovtseva, N. A. Koziolova, A. I. Chernyavina, I. M. Shatunova   +3 more
doaj  

The Effects of a 48-Hour Fasting Period on Metabolic Markers During Exercise and Recovery in Male Combat Sports Athletes

Baltic Journal of Sport and Health Sciences
Purpose: Fasting strategies have gained increasing attention in sports science due to their potential effects on metabolic responses and athletic performance.
Asya Culhaoglu, Nerijus Eimantas, Rima Solianik, Berta Ylaitė, Marius Brazaitis   +4 more
doaj   +1 more source

Dynamic alterations in gene expression after Wnt-mediated induction of avian neural crest [PDF]

, 2005
The Wnt signaling pathway is important in the formation of neural crest cells in many vertebrates, but the downstream targets of neural crest induction by Wnt are largely unknown. Here, we examined quantitative changes in gene expression regulated by Wnt-
Bronner, Marianne E., Taneyhill, Lisa A.
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Distinct subpopulations of enteric neuronal progenitors defined by time of development, sympathoadrenal lineage markers and Mash-1-dependence [PDF]

, 1996
Enteric and sympathetic neurons have previously been proposed to be lineally related. We present independent lines of evidence that suggest that enteric neurons arise from at least two lineages, only one of which expresses markers in common with ...
Anderson, D. J., Blaugrund, E., Gershon, M. D., Lo, L., Pham, T. D., Sommer, L., Tennyson, V. M.   +6 more
core  

Twenty-Four-Hour Heart Rate and Blood Pressure Are Additive Markers of Left Ventricular Mass in Hypertensive Subjects [PDF]

American Journal of Hypertension, 2006
We investigated whether mean heart rate (HR(24)) and blood pressure (BP) parameters during 24-h ambulatory BP monitoring (ABP) are independent or additive markers of left ventricular (LV) mass in subjects with newly diagnosed, untreated hypertension.A total of 250 patients (40% women, 60% men; mean age 59.6 +/- 11 years) with essential hypertension who
Zakopoulos, NA, Ikonomidis, I, Vemmos, KN, Manios, E, Spiliopoulou, I, Tsivgoulis, G, Spengos, K, Psaltopoulou, D, Mavrikakis, M, Moulopoulos, SD   +9 more
openaire   +3 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Procalcitonin, Interleukin-1, Interleukin-10, Interleukin-13 and Tumor necrosis factor-alpha predictive value in the diagnosis of sepsis [PDF]

Kirkuk Journal of Science, 2017
The present study is aimed to evaluate the role of some markers in the diagnosis of sepsis among SIRS (systemic inflammatory response syndrome) patients. The study included 180 patients with SIRS criteria within 24 hour of admission.
Ansam Mohammad H, Zainalabdeen A. Abdulla   +1 more
doaj   +1 more source