Results 101 to 110 of about 2,837,475 (309)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
The Housing Market(s) of San Diego [PDF]
This paper uses an assignment model to understand the cross section of house prices within a metro area. Movers’ demand for housing is derived from a lifecycle problem with credit market frictions.
Martin Schneider +2 more
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Alternative Methods of Increasing the Precision of Weighted Repeat Sales House Prices Indices* [PDF]
, 2004 Weighted repeat sales house price indices have become one of the primary indicators used to identify housing market conditions and to estimate the amount of equity homeowners have gained through house price appreciation.
Dreiman, Michelle H +1 more
core +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
The Determinants of House Prices and Construction: An Empirical Investigation of the Swiss Housing Economy [PDF]
This paper studies the Swiss housing price determinants. The Swiss housing economy is reproduced by employing a macro-series from the last seventeen years and constructing a vector-autoregressive model.
Karol Jan Borowiecki
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Arts Integration as a Pathway to Unity in the Community: The (Ongoing) Journey of Pillsbury House + Theatre [PDF]
, 2014 This report is a 2013 study of how a nonprofit theater and a social service agency that happened to reside in the same building rediscovered their shared history as a 19th century Settlement House, and unified operations to become a 21st Century Center ...
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Using survey data to study capitalization of local public services [PDF]
We use surveys in which respondents evaluate local amenities in Norway to compute proxy variables for the quality of local public services as well as other local amenities relevant to location decisions.
Bjørg Langset +3 more
core
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source