Results 121 to 130 of about 2,837,475 (309)

Purchasing Power: The Corporate-White House Alliance to Pass the China Trade Bill Over the Will of the American People [PDF]

open access: yes, 2000
The passage of China Permanent Normal Trade Relations (PNTR) by the U.S. House of Representatives in late May 2000 over the overwhelming will of the American people was the result of the most forceful and aggressive corporate legislative campaign in ...
Jessica Roach   +3 more
core  

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Minimally Clinically Important Difference of the Clinical Assessment Scale in Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The Clinical Assessment Scale in Autoimmune Encephalitis (CASE) tracks disease severity in autoimmune encephalitis (AE), but no threshold for significant change exists. We aimed to determine the minimally clinically important difference (MCID) for CASE.
Yihui Goh   +8 more
wiley   +1 more source

Developing an online application for automating "house of quality" construction for QFD analysis

open access: yesАрхитектура, строительство, транспорт
QFD analysis is among the few quality tools that can encompass a wide range of processes in product manufacturing. This analysis enables effective planning for the implementation of various technical support tools, which complement each other in ...
M. S. Ostapenko   +2 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Improving mealtimes for patients and staff within an eating disorder unit: the next chapter

open access: yesBMJ Open Quality, 2022
Hayley Trueman   +4 more
doaj   +1 more source

The Effect of School Quality on Residential Sales Price [PDF]

open access: yes
This study seeks to find the extent to which various measures of public school quality are capitalized into house prices after the No Child Left Behind Act (2001). Individual residential sales in Cuyahoga County, Ohio for 2000 and 2005 are analyzed as to
Robert A. Simons, Youngme Seo
core  

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

Casa da qualidade e qualidade da informação: revisão sistemática

open access: yesPerspectivas em Ciência da Informação
RESUMO As informações são consideradas matéria-prima para criação de conhecimento, este que por sua vez agrega valor às organizações, proporciona inovação e dá destaque para as organizações.
Fernanda dos Santos, Lia Caetano Bastos
doaj   +1 more source

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