JCPP Advances, EarlyView.Abstract Background Childhood adversity increases psychosis risk, but the biological mechanisms responsible remain elusive. A possible but underexplored pathway involves altered pubertal and grey matter (GM) development. Methods In youth from the Adolescent Brain Cognitive Development study (N = 3462), we investigated the effect of adversity at age 9 ...
Megan Thomas +3 more
wiley +1 more source
Glucose as fuel for HPA axis regulation: A narrative review on energy metabolism, stress reactivity, and early life adversity. [PDF]
Compr PsychoneuroendocrinolPruessner JC, Meier M.
europepmc +1 more source
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.ABSTRACT Rapid phenotypic change may be mediated by intergenerational transmission of early developmental experiences. In birds, exposure to glucocorticoids during early development can alter global DNA methylation and gene expression. However, DNA methylation is labile, and it is currently unclear whether the impacts of stress suffered during juvenile
Anna Miltiadous +5 more
wiley +1 more source
Integrated Immunotherapy Target Atlas for Ewing Sarcoma. [PDF]
Cancer Genomics ProteomicsGoldman C.
europepmc +1 more source
Characterising Vento Norte Downslope Windstorms and Their Thermal Impacts in Southern Brazil
International Journal of Climatology, EarlyView.Using 20 years of hourly INMET observations in Santa Maria (southern Brazil), we identify 189 Vento Norte (VNOR) downslope windstorms, ~72% in winter, marked by abrupt warming, drying and strong northerly gusts. Across five biometeorological indices (TEFW, TDI, THI, HDI, Humidex), VNOR hours consistently show significantly higher thermal discomfort ...
Cinara Ewerling da Rosa +5 more
wiley +1 more source
Central neuroendocrine dysregulation in ischaemic stroke sequelae: pathophysiological mechanisms-a narrative review. [PDF]
Front Hum NeurosciGong H, Liu D, Wang XZ, Rao JS, Du XX.
europepmc +1 more source
International Journal of Climatology, EarlyView.The Galápagos Archipelago's near‐surface climate is primarily influenced by interannual El Niño‐Southern Oscillation variability, with no statistical evidence for long‐term trends in air temperature, humidity, or precipitation. While tropospheric warming and increased atmospheric stability are observed, these trends are largely decoupled from near ...
Benjamin Schmidt +6 more
wiley +1 more source
Acupuncture Modulation of the Microbiota-Gut-Brain Axis in Major Depressive Disorder: Integrative Mechanisms, Emerging Evidence, and Future Therapeutic Perspectives. [PDF]
Neuropsychiatr Dis TreatZhang J +6 more
europepmc +1 more source
A Zonal‐Meridional Projection Method for Quantifying Global Land‐Ocean Moisture Transport
International Journal of Climatology, EarlyView.We present a physically consistent and computationally efficient method to quantify global coastal moisture transport by projecting vertically integrated moisture flux onto signed land–ocean boundary segments. The signed projection naturally distinguishes ocean‐to‐land inflow and land‐to‐ocean outflow without explicit directional classification ...
Chong Zhang +2 more
wiley +1 more source
Stress and HPA axis dysfunction impact diverse epilepsy outcomes including psychiatric comorbidities and SUDEP. [PDF]
Epilepsy ResJoyal KG, Maguire JL.
europepmc +1 more source