Time‐dependent association between prenatal hair glucocorticoid levels and child behavior problems
Background Child internalizing and externalizing behavioral problems are highly prevalent psychiatric symptoms worldwide, for which maternal prenatal stress is a known risk factor. However, underlying neuroendocrine mechanisms remain largely unclear. We investigated whether maternal hair cortisol (HCC) and cortisone concentration (HCNC) are associated ...
Richard G. Künzel +11 more
wiley +1 more source
Activation of the HPA Axis Does Not Explain Nonresponsiveness to GLP-1R Agonist Treatment in Individuals With Type 2 Diabetes. [PDF]
Tokgöz S +8 more
europepmc +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth +5 more
wiley +1 more source
Quercetin attenuates cisplatin-induced fatigue through mechanisms associated with the regulation of the HPA axis and MCP-1 signaling. [PDF]
Chuang CH, Tai YA, Wu TJ, Ho YJ, Yeh SL.
europepmc +1 more source
The Role of Oxidative Stress in Periodontitis
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
wiley +1 more source
This mini‐review describes the pathophysiology of the disrupted hypothalamic–pituitary–adrenal axis in dogs, and probably cats, with the MDR1 (ABCB1) mutation, ABCB1‐1Δ in dogs and ABCB11930‐1931del TC in cats. Clinical consequences in affected animals are discussed and therapeutic interventions to consider are presented.
K. L. Mealey
wiley +1 more source
Perioperative Complications Associated with Routine Preoperative Glucocorticoid Use Among Patients Undergoing Pituitary Surgery with Normal Preoperative HPA Axis: A Retrospective Cohort Study. [PDF]
Magnaye FM, Paz-Pacheco E.
europepmc +1 more source
ABSTRACT Fibromyalgia is a chronic pain condition characterised by widespread pain, sleep disturbances and mood disorders, often leading to significant functional impairment. Although sleep problems are recognised as important contributors to fibromyalgia symptoms, the mechanisms linking sleep disturbances, psychological factors and functional ...
Kristoffer Bothelius +2 more
wiley +1 more source
Individualized identification value of stress-related network structural-functional properties and HPA axis reactivity for subthreshold depression. [PDF]
He Y, Zhao B, Liu Z, Hu Y, Song J, Wu J.
europepmc +1 more source

