Results 171 to 180 of about 80,068 (296)

HPA axis function in mood disorders

Mood disorders rank among the leading causes of disability worldwide, and are characterized by biological, emotional, psychological and cognitive symptoms. The monoamine hypothesis of depression fails to provide a comprehensive theory to account for this
Watson S, Mackin P
core  

Retinal ganglion cell degeneration in glaucoma disrupts HPA axis temporal organization and dampens corticosterone production. [PDF]

J Neuroendocrinol
Barsanele PS, da Silva JJ, Cortes BFDS, de Oliveira Furtado EM, Cipolla-Neto J, de Assis LVM, Poletini MO, Moraes MN.   +7 more
europepmc   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Developmental ethanol exposure and its impact on behaviour and HPI axis activity of zebrafish

, 2015
Ethanol exposure during pregnancy is one of the leading causes of preventable birth defects, leading to a range of symptoms collectively known as fetal alcohol spectrum disorder (FASD).
Baiamonte, Matteo
core  

Correction: Ocimum tenuiflorum extract (HOLIXERTM): Possible effects on hypothalamic-pituitary-adrenal (HPA) axis in modulating stress. [PDF]

PLoS One
C M MG, Murugan SK, Bethapudi B, Purusothaman D, Mundkinajeddu D, D'Souza P.   +5 more
europepmc   +1 more source

Optimizing acupuncture dosing for hormone therapy‐induced hot flashes in cancer patients: A regression‐based analysis and narrative review

Precision Medical Sciences, EarlyView.
Our analysis reveals a clear dose–response relationship between acupuncture sessions and the reduction of hormone therapy‐induced hot flashes. A threshold of approximately 10 sessions establishes a robust quantitative benchmark for achieving clinically meaningful neuro‐autonomic modulation and symptom relief.
Jiaming Cui, Xinyao Wei, Lulu Bin, Shaoxin Sun, Yu Liu, Tao Yang, Zhishun Liu, Jiani Wu   +7 more
wiley   +1 more source

From herbal hope to hormonal havoc: chronic ashwagandha use and HPA axis suppression. [PDF]

Endocrinol Diabetes Metab Case Rep
Javid J, Kunnuru SR, Anne B, Muskan S.
europepmc   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

Chronic Stress and Autoimmunity: The Role of HPA Axis and Cortisol Dysregulation. [PDF]

Int J Mol Sci
Nunez SG, Rabelo SP, Subotic N, Caruso JW, Knezevic NN.   +4 more
europepmc   +1 more source

Patterns in integrative medicine usage among pediatric patients in a disorders of gut–brain interaction clinic

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Austin VonAxelson, Cincinnati Children's Gastroenterology and Nutrition Research Group, Kahleb Graham, Megan Miller, Jesse Li, Hanson Ton, Emily Romantic, Kathryn Hitchcock, Rashmi Sahay, Neha Santucci   +9 more
wiley   +1 more source