Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley +1 more source
Examining the Effects of Induced Rumination on HPA-Axis Regulation
Rumination impacts a persons' ability to cope with stress and may prolong or intensify the HPA-axis stress response. Prior studies have shown that ruminative tendencies are associated with greater HPA-axis response to laboratory stressors.
Shull, Alexa
core
Prenatal Stress Induces Changes in Behavior, HPA Axis, Inflammation, and Oxidative Stress in Adult Rats Offspring. [PDF]
Aguiar-Geraldo JM +7 more
europepmc +1 more source
ABSTRACT Ashwagandha (Withania somnifera) has been recognized for enhancing physical strength, mental well‐being, and overall vitality. Despite its long‐standing use across generations, some clinical reports have noted occasional adverse events. This study compared the safety and tolerability of Ashwagandha Root Extract (ARE) in healthy adults.
Ketan Pakhale +4 more
wiley +1 more source
Near‐resonant excitation of the Adriatic barotropic modes: The seiche events of December 2019
This study examines severe flooding in the northern Adriatic Sea in December 2019, which existing forecasting systems failed to predict. Analysis of wind and sea‐level data, alongside reanalysis datasets and a high‐resolution hydrodynamic model, revealed a wind‐induced resonance mechanism.
Marco Bajo +3 more
wiley +1 more source
The mechanisms by which hypothalamic neuroinflammation induced by neonatal cerebral ischemia-hypoxia leads to decreased thymic function via the HPA axis. [PDF]
Liu GG +10 more
europepmc +1 more source
How consistently do ensemble prediction systems represent the growth of atmospheric uncertainty?
Spread‐based diagnostics calculated for 12 ensemble prediction systems are compared to understand the consistency with which they represent atmospheric uncertainty growth. Good correlation between all these systems is found in the extratropics for a lead time range from 48 hr to between 96 hr and 192 hr.
Douglas Wood +3 more
wiley +1 more source
The Convergence of Early-Life Stress and Autism Spectrum Disorder on the Epigenetics of Genes Key to the HPA Axis. [PDF]
Han E +4 more
europepmc +1 more source
Daily time series of zonal‐mean zonal wind (m·s−1) at 10 hPa and 60° N from 1950 to 2021 from the ERA5 reanalysis. This shows huge variability in some seasons and very little in others. We provide evidence that high‐level observations, radiosonde and satellite, are more important during the extended winter season with its very large variability ...
Bruce Ingleby, Inna Polichtchouk
wiley +1 more source
The HPA axis and kynurenine pathway: exploring the role of stress and neuroinflammation in treatment-resistant depression. [PDF]
Bose MM +4 more
europepmc +1 more source

