Results 221 to 230 of about 802,913 (283)

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

Antidepressant and Cognitive-Enhancing Effects of <i>Stewartia pseudocamellia</i> Maxim. Leaves in Chronic Unpredictable Mild Stress-Induced Mice Through HPA Axis Regulation and the BDNF/TrkB Pathway. [PDF]

Pharmaceuticals (Basel)
Heo YM, Lee HL, Choi HJ, Ju YH, Na HR, Heo HJ.   +5 more
europepmc   +1 more source

KYNU in Gastric Cancer Cells Promotes Tumor Progression by Influencing Macrophage Polarization Via PF4

Cancer Science, EarlyView.
KYNU is upregulated in gastric cancer cells and activates the PI3K/Akt pathway, leading to PF4 secretion. PF4 drives nonclassical macrophage polarization with high expression of S100A8 and MMP7, which promotes tumor proliferation, migration, and invasion while suppressing phagocytosis, thereby accelerating gastric cancer progression.
Xilun Cui, Changfeng Li, Yuanda Liu, Chang Liu, Wei Yang   +4 more
wiley   +1 more source

Correction to: Do stress hormones influence choice? A systematic review of pharmacological interventions on the HPA axis and/or SAM system. [PDF]

Soc Cogn Affect Neurosci
europepmc   +1 more source

Antidepressant-like Effects of <i>Garcinia nigrolineata</i> Resin Extract in a Chronic Mild Stress Mouse Model: Modulation of Monoaminergic and HPA-Axis Pathways. [PDF]

Plants (Basel)
Chotritthirong Y, Sumanont Y, Daodee S, Mading A, Boonyarat C, Khamphukdee C, Kumla D, Maneenet J, Matsumoto K, Kijjoa A, Awale S, Monthakantirat O.   +11 more
europepmc   +1 more source

Adrenal rather than central dysfunction limits hypothalamic-pituitary-adrenal axis recovery after chronic glucocorticoid treatment in male mice. [PDF]

Endocrinology
Gaston LS, Jorgensen BC, Friedman HR, Sherman MS, Majzoub JA.   +4 more
europepmc   +1 more source

Comparative Analysis of HPA-Axis Dysregulation and Dynamic Molecular Mechanisms in Acute Versus Chronic Social Defeat Stress. [PDF]

Int J Mol Sci
Yang J, Jia Y, Guo T, Zhang S, Huang J, Lu H, Li L, Xu J, Liu G, Xiao K.   +9 more
europepmc   +1 more source

Letter to the Editor on the article, '<i>Perioperative Complications Associated with Routine Preoperative Glucocorticoid Use Among Patients Undergoing Pituitary Surgery with Normal Preoperative HPA Axis: A Retrospective Cohort Study</i>' by Magnaye and Paz-Pacheco, published in JAFES Vol. 40. No. 1. [PDF]

J ASEAN Fed Endocr Soc
Fatimah E, Usman S, Khan MAF.
europepmc   +1 more source