Results 241 to 250 of about 927,205 (366)

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Green HPLC-Fluorescence detection method for concurrent analysis of Tamsulosin hydrochloride and Tolterodine tartrate in dosage forms and biological fluids. [PDF]

Sci Rep
Derayea SM, Badr El-Din KM, Ahmed AS, Oraby M, Abdelshakour MA.   +4 more
europepmc   +1 more source

Separation and determination of vitamin B6 derivatives by reversed-phase HPLC.

, 1986
Haruhito Tsuge, Toshikatsu Oda, Hideo Miyata   +2 more
openalex   +2 more sources

Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles

Advanced Science, EarlyView.
Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon, Patricia Perez Schmidt, Nicolo Panini, Francesca Caruso, Martina B. Violatto, Naths Grazia Sukubo, Alberto Martinez‐Serra, Charlotte Blanche Ekalle‐Soppo, Annalisa Morelli, Giulia Yuri Moscatiello, Chiara Grasselli, Alessandro Corbelli, Fabio Fiordaliso, Joe Kelk, Laura Petrosilli, Giuseppe d'Orazio, Ruth Mateu Ferrando, Ariadna Verdaguer Ferrer, Cristina Fornaguera, Luigi Lay, Stefano Fumagalli, Sandro Recchia, Marco P. Monopoli, Laura Polito, Paolo Bigini, Giovanni Sitia   +25 more
wiley   +1 more source

Head-to-Head Comparison of the <i>in Vivo</i> Performance of Highly Reactive and Polar ¹⁸F-Labeled Tetrazines. [PDF]

Mol Pharm
Hvass L, Müller M, Staudt M, García-Vázquez R, Gustavsson TK, Shalgunov V, Jørgensen JT, Battisti UM, Herth MM, Kjaer A.   +9 more
europepmc   +1 more source

HPLC Method for the Analysis of Cyproterone Acetate in Tablets

, 1987
James C. Scott, Richard Soltero
openalex   +1 more source

Advancing the Identification of Bioactive Molecules and the Construction of a Synergistic Drug Delivery System in Combating Lung Injury

Advanced Science, EarlyView.
Traditional Chinese Medicine (TCM), while holistic and historically esteemed, faces challenges in “miracle cures” due to slow onset, long cycles, and difficulty controlling quality. This study obtains the active ingredients, glabridin (GLA) and puerarin (PUE), from Ge‐Gen Decoction (GGD), developing a safe and effective drug delivery system, GLA‐PUE ...
Jianhong Qi, Yanxia Wang, Huan Chen, Kaitian Wu, Pei Zhou, Yue Dou, Bingqi Xiong, Wei Zhou   +7 more
wiley   +1 more source

Preclinical Pharmacokinetic Assessment of a Promising Vasorelaxant, Analgesic, and Anti-Inflammatory Prototype 5-[1-(4-Fluorophenyl)-1H-pyrazol-4-yl]-2H-tetrazole (LQFM020) Through Selective Bioanalytical HPLC-PDA-Based Method. [PDF]

Biomed Chromatogr
de Oliveira LP, de Oliveira Neto JR, de Oliveira TS, Naves LM, Marques SM, Cruz AC, Fajemiroye JO, Pedrino G, Lião LM, Menegatti R, da Cunha LC.   +10 more
europepmc   +1 more source

Plant-pathogen interactions during infection process of asparagus with Fusarium spp.

Open Life Sciences, 2013
Waśkiewicz Agnieszka, Irzykowska Lidia, Drzewiecka Kinga, Bocianowski Jan, Dobosz Bernadeta, Weber Zbigniew, Karolewski Zbigniew, Krzyminiewski Ryszard, Goliński Piotr   +8 more
doaj   +1 more source

Developing Quorum Sensing‐Based Collaborative Dynamic Control System in Halomonas TD01

Advanced Science, EarlyView.
A standardized and streamlined inducer‐free quorum sensing (QS)‐based collaborative dynamic control pattern is developed for sufficient gene expression control in Halomonas TD by mixing two engineered cells, cells A and B. Proof‐of‐concept studies are designed to test the dynamic control performance in mixed cultures in fed‐batch conditions.
Yi‐Na Lin, Yu‐Xi Li, Ye Zheng, Yi‐Hao Deng, Kai‐Xuan Liu, Yue Gan, Hao Li, Jun Wang, Jia‐Wen Peng, Rui‐Zhe Deng, Huai‐Ming Wang, Hui Wang, Jian‐Wen Ye   +12 more
wiley   +1 more source