Results 21 to 30 of about 9,143 (202)

Critical evaluation of HPV16 gene copy number quantification by SYBR green PCR [PDF]

, 2008
Background: Human papilloma virus (HPV) load and physical status are considered useful parameters for clinical evaluation of cervical squamous cell neoplasia. However, the errors implicit in HPV gene quantification by PCR are not well documented. We have
Ng, G, Teschendorff, A, Stanley Margaret, Stanley, M, Coleman, N, Ng Grace, Herdman Michael T, Herdman, MT, Pett, MR, Foster, N, Roberts Ian, Teschendorff Andrew, Coleman Nicholas, Roberts, I, Pett Mark R, Foster Nicola   +15 more
core   +1 more source

Epidemiological Study of Anti-HPV16/18 Seropositivity and Subsequent Risk of HPV16 and -18 Infections [PDF]

JNCI Journal of the National Cancer Institute, 2010
Infection with human papillomavirus (HPV) 16 or HPV18 elicits an antibody response, but whether the elicited antibodies protect women against subsequent infection by a homologous HPV type compared with seronegative women is unknown.Study participants were women aged 18-25 years at enrollment in the control group of the ongoing National Cancer Institute-
Mahboobeh, Safaeian, Carolina, Porras, Mark, Schiffman, Ana Cecilia, Rodriguez, Sholom, Wacholder, Paula, Gonzalez, Wim, Quint, Leen-Jan, van Doorn, Mark E, Sherman, Valérie, Xhenseval, Rolando, Herrero, Allan, Hildesheim   +11 more
openaire   +2 more sources

AKT1 loss correlates with episomal HPV16 in vulval intraepithelial neoplasia. [PDF]

, 2012
Anogenital malignancy has a significant association with high-risk mucosal alpha-human papillomaviruses (alpha-PV), particularly HPV 16 and 18 whereas extragenital SCC has been linked to the presence of cutaneous beta and gamma-HPV types. Vulval skin may
Harwood Catherine A., Carolyn R Byrne, Karin J Purdie, Byrne, CR, Ekeowa-Anderson, AL, Purdie, Karin J, Jeffrey M. Arbeit (159402), Karin J. Purdie (159384), Jeffrey M Arbeit, O'Shaughnessy Ryan F. L., Byrne Carolyn R., Ekeowa-Anderson Arucha L., Gibbon, K, Ekeowa-Anderson, Arucha L, Byrne, Carolyn R, O'Shaughnessy, RFL, Ryan F L O'Shaughnessy, O'Shaughnessy, RF, Harwood, CA, Purdie Karin J., Arbeit, Jeffrey M, Arucha L. Ekeowa-Anderson (159376), Harwood, Catherine A, Karen Gibbon, Arbeit Jeffrey M., Arucha L Ekeowa-Anderson, Gibbon, Karen, Karen Gibbon (159391), Catherine A. Harwood (159410), Purdie, KJ, Ryan F. L. O'Shaughnessy (159418), Catherine A Harwood, Arbeit, JM, Gibbon Karen, O\u27Shaughnessy, Ryan F. L., Carolyn R. Byrne (159397)   +35 more
core   +1 more source

HPV16 synthetic long peptide (HPV16-SLP) vaccination therapy of patients with advanced or recurrent HPV16-induced gynecological carcinoma, a phase II trial [PDF]

Journal of Translational Medicine, 2013
Abstract Background Human papilloma virus type 16 (HPV16)-induced gynecological cancers, in particular cervical cancers, are found in many women worldwide. The HPV16 encoded oncoproteins E6 and E7 are tumor-specific targets for the adaptive immune system permitting the development of an HPV16-synthetic long peptide ...
Poelgeest, M.I.E. van, Welters, M.J.P., Esch, E.M.G. van, Stynenbosch, L.F.M., Kerpershoek, G., Meerten, E.L.V. van, Hende, M. van den, Lowik, M.J.G., Berends-van der Meer, D.M.A., Fathers, L.M., Valentijn, A.R.P.M., Oostendorp, J., Fleuren, G.J., Melief, C.J.M., Kenter, G.G., Burg, S.H. van der   +15 more
openaire   +5 more sources

Characterization of human papillomavirus (HPV) 16 E6 seropositive individuals without HPV-associated malignancies after 10 years of follow-up in the UK Biobank

EBioMedicine, 2020
Background: Antibodies against the HPV16 oncoprotein E6 are promising biomarkers for HPV16-driven oropharyngeal cancer (HPV16-OPC) due to their high sensitivity and specificity, and prospective manifestation. In previous studies, 0•7% of controls without
Nicole Brenner, Alexander J. Mentzer, Michael Hill, Rachael Almond, Naomi Allen, Michael Pawlita, Tim Waterboer   +6 more
doaj   +1 more source

HPV16-positive OPSCC patients.

, 2023
Saliva is an emerging source of disease biomarkers, particularly for cancers of the head and neck. Although analysis of cell-free DNA (cfDNA) in saliva holds promise as a liquid biopsy for cancer detection, currently there are no standardized ...
Patricia J. Brooks (10778195), Scott V. Bratman (6943946), Ethan Z. Malkin (15389231), Steven De Michino (15389234)   +3 more
core   +1 more source

SOX2 as a New Regulator of HPV16 Transcription [PDF]

Viruses, 2017
Persistent infections with high-risk human papillomavirus (HPV) constitute the main risk factor for cervical cancer development. HPV16 is the most frequent type associated to squamous cell carcinomas (SCC), followed by HPV18. The long control region (LCR) in the HPV genome contains the replication origin and sequences recognized by cellular ...
Imelda Martínez-Ramírez, Víctor Del-Castillo-Falconi, Irma Mitre-Aguilar, Alfredo Amador-Molina, Adela Carrillo-García, Elizabeth Langley, Alejandro Zentella-Dehesa, Ernesto Soto-Reyes, Alejandro García-Carrancá, Luis Herrera, Marcela Lizano   +10 more
openaire   +3 more sources

HPV16 E1 dysregulated cellular genes involved in cell proliferation and host DNA damage: A possible role in cervical carcinogenesis.

PLoS ONE, 2021
HPV16 is the most prominent cause of cervical cancer. HPV16 E1, a helicase required for HPV replication exhibits increased expression in association with cervical cancer progression, suggesting that E1 has a similar effect on the host as the HPV16 E6 and
Fern Baedyananda, Arkom Chaiwongkot, Shankar Varadarajan, Parvapan Bhattarakosol   +3 more
doaj   +1 more source

Examination of MHC-1 Expression by J774 Macrophage Cells Treated with Recombinant Protein HIV-1 Tat 49-59 / HPV16, 18, 6, 11 E7 In Vitro

Journal of Mazandaran University of Medical Sciences, 2021
Background and purpose: Human papillomavirus (HPV) is one of the infectious agents that causes genital and non-genital warts and skin cancers in humans.
Tahoora Mousavi, Reza Valadan, Alireza Rafiei, Mohammadreza Haghshenas   +3 more
doaj  

A Role for HPV16 E5 in Cervical Carcinogenesis [PDF]

Cancer Research, 2010
Abstract A subset of the mucosotropic human papillomaviruses (HPV), including HPV16, are etiologic agents for the vast majority of cervical cancers, other anogenital cancers, and a subset of head and neck squamous cell carcinomas. HPV16 encodes three oncogenes: E5, E6, and E7.
John P, Maufort, Anny, Shai, Henry C, Pitot, Paul F, Lambert   +3 more
openaire   +2 more sources