Results 91 to 100 of about 3,351,166 (211)
Hsp70 in mitochondrial biogenesis [PDF]
, 1994 The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology, Hsp70 proteins appear to elicit their effects by interacting with polypeptides that present domains which exhibit non ...
Stuart, Rosemary A. +2 more
core +1 more source
Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies
Advanced Science, Volume 13, Issue 38, 9 July 2026.In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang +4 more
wiley +1 more source
Enhanced levels of cold shock proteins in Listeria monocytogenes LO28 upon exposure to low temperature and high hydrostatic pressure [PDF]
, 2002 Listeria monocytogenes is a psychrotrophic food-borne pathogen that is problematic for the food industry because of its ubiquitous distribution in nature and its ability to grow at low temperatures and in the presence of high salt concentrations.
Karatzas, Andreas K. +7 more
core +1 more source
PLoS ONE, 2015 To search for reliable biomarkers and drug targets for management of hepatocellular carcinoma (HCC), we performed a global proteomic analysis of a pair of HCC cell lines with distinct differentiation statuses using 2-DE coupled with MALDI-TOF MS.
Ruo-Chiau Wang +6 more
doaj +1 more source
Cells, 2018 The incidence of colorectal cancer (CRC) has significantly increased in recent decades, and this disease has become an important health issue worldwide. Currently, there is no useful prognostic or diagnostic biomarker for CRC.
Chien-Yu Huang +4 more
doaj +1 more source
Heat Shock Proteins in Veterinary Medicine and Sciences.
, 2017 Not AvailableChicken has been selected for higher production performance over the years and are highly sensitive to changes in their environment. The average global temperature has increased over the century and is further expected to rise. In open house
Shanmugam Murugesan, Rajkumar Ullengala, and Vinoth Amirthalingam
core
FoodsThis research explored the potential role of various heat-shock proteins (HSPs) in the determination of postmortem metabolism and the development of meat quality of normal, atypical DFD, and typical DFD beef. Beef longissimus thoracis muscle samples were
Muawuz Ijaz +4 more
doaj +1 more source
Ultraviolet B-Mediated Phosphorylation of the Small Heat Shock Protein HSP27 in Human Keratinocytes
Journal of Investigative Dermatology, 2000 Exposure of human keratinocytes to environmental stress is known to induce changes in the expression, phosphorylation, and subcellular relocalization of the 27 kDa heat shock protein. This study demonstrates that ultraviolet B (280-320 nM) irradiation with physiologic doses induces a dose-dependent phosphorylation of 27 kDa heat shock protein ...
Wong, Jon W. +6 more
openaire +2 more sources
Changes in HSP gene and protein expression in natural scrapie with brain damage
Veterinary Research, 2011 Heat shock proteins (Hsp) perform cytoprotective functions such as apoptosis regulation and inflammatory response control. These proteins can also be secreted to the extracellular medium, acting as inflammatory mediators, and their chaperone activity ...
Serrano Carmen +11 more
doaj +1 more source
PLoS ONE, 2012 A high percentage of oesophageal adenocarcinomas show an aggressive clinical behaviour with a significant resistance to chemotherapy. Heat-shock proteins (HSPs) and glucose-regulated proteins (GRPs) are molecular chaperones that play an important role in
Julia Slotta-Huspenina +12 more
doaj +1 more source