Results 71 to 80 of about 3,351,166 (211)
Reumatismo, 2003 Under stress cells and tissues perform a series of physiologic adjustments, including the heat shock protein production (Hsp), these proteins play a role as molecular chaperons, they are divided in five main families: Hsp27, Hsp 60, Hsp70, Hsp90 and ...
R. Villalobos-Hurtado +3 more
doaj +1 more source
Experimental Physiology, EarlyView.Abstract Cold‐water immersion (CWI) is among the most widely used post‐exercise recovery modalities in elite sport and clinical rehabilitation, yet a fundamental paradox now emerges from the evidence: the same protocols that accelerate parasympathetic reactivation and reduce perceived muscle soreness also suppress the molecular and cellular machinery ...
Jose Francisco Tornero‐Aguilera +8 more
wiley +1 more source
Heat shock protein 27 phosphorylation state is associated with cancer progression
Frontiers in Genetics, 2014 Understanding the mechanisms that control stress-induced survival is critical to explain how tumors frequently resist to treatment and to improve current anti-cancer therapies.
Maria eKatsogiannou +11 more
doaj +1 more source
Dephosphorylation of the small heat shock protein Hsp27 in vivo by protein phosphatase 2A.
Journal of Biological Chemistry, 1994 The phosphorylation of the Hsp27 complex is rapidly altered in MRC-5 cells when they are exposed to mitogens, cytokines, stress, or serine/threonine protein phosphatase inhibitors. Here we performed experiments to identify which cellular protein phosphatase (PP1, PP2A, or PP2B) is responsible for the in vivo phosphorylation/dephosphorylation of Hsp27 ...
Cairns, J. +4 more
openaire +2 more sources
Phase Separation, Material State, and Condensate Fate in Mammalian Autophagy
Advanced Science, Volume 13, Issue 54, 28 September 2026.ABSTRACT Biomolecular phase separation has emerged as a key organizing principle in macroautophagy (hereafter autophagy). In mammalian cells, phase‐separated condensates not only serve as substrates for selective degradation, but also act as dynamic platforms for cargo recognition, signaling integration, and autophagosome assembly.
Yuanqiang Lin +8 more
wiley +1 more source
Heat Shock Proteins in Fish Health and Diseases: A Pharmacological Perspective
, 2017 Disease outbreaks are considered one of the largest constraints for the sustainable development of the aquaculture sector. Though applications of antibiotics manage to control and prevent infectious microbial diseases, however, its extensive uses have ...
Parisa Norouzitallab +5 more
core +1 more source
Scientific Reports, 2023 Estimating the age and vitality of human skin wounds is essential in forensic practice, and the use of immunohistochemical parameters in this regard remains a challenge.
Siying Zhang +12 more
doaj +1 more source
The regulation of stem cell fate and its application in neural regeneration
Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He +3 more
wiley +1 more source
Scientific Reports, 2023 Previous studies have proposed that heat shock proteins 27 (HSP27) and its anti-HSP27 antibody titers may play a crucial role in several diseases including cardiovascular disease. However, available studies has been used simple analytical methods.
Nasrin Talkhi +6 more
doaj +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.Polystyrene nanoplastic particles (NPPs) interact with serum proteins, establishing nano‐bio interactions and triggering ROS‐mediated macrophage toxicity in THP‐1 cells, characterized by oxidative stress, mitochondrial dysfunction, apoptosis and stress‐signaling.
Balamurali Mahalakshmi +3 more
wiley +1 more source