Results 61 to 70 of about 9,646 (179)

Forensic application of epidermal expression of HSP27 and HSP70 for the determination of wound vitality in human compressed neck skin

Scientific Reports, 2023
Estimating the age and vitality of human skin wounds is essential in forensic practice, and the use of immunohistochemical parameters in this regard remains a challenge.
Siying Zhang, Yuko Ishida, Akiko Ishigami, Mizuho Nosaka, Yumi Kuninaka, Haruki Yasuda, Ayumi Kofuna, Jumpei Matsuki, Miyu Osako, Wei Zhang, Akihiko Kimura, Fukumi Furukawa, Toshikazu Kondo   +12 more
doaj   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, Volume 293, Issue 13, Page 3717-3757, July 2026.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Prediction of serum anti-HSP27 antibody titers changes using a light gradient boosting machine (LightGBM) technique

Scientific Reports, 2023
Previous studies have proposed that heat shock proteins 27 (HSP27) and its anti-HSP27 antibody titers may play a crucial role in several diseases including cardiovascular disease. However, available studies has been used simple analytical methods.
Nasrin Talkhi, Mehdi Jabbari Nooghabi, Habibollah Esmaily, Saba Maleki, Mojtaba Hajipoor, Gordon. A. Ferns, Majid Ghayour-Mobarhan   +6 more
doaj   +1 more source

At the Edge of Survival: Exploring the Frontiers of Tardigrade Extreme Stress Tolerance

Molecular Ecology, Volume 35, Issue 14, July 2026.
ABSTRACT Tardigrades possess extraordinary resilience to extreme environmental conditions, including near‐complete desiccation, severe levels of radiation, the vacuum of space and extreme sub‐zero temperatures. Despite significant interest in their survival strategies, the molecular mechanisms underlying their survival during extreme stresses have ...
Maria Kamilari, Frida Løkkegaard Pust, Andrea Marcantognini, Ask Møbjerg, Ricardo Cardoso Neves, Morten Schiøtt, Nadja Møbjerg   +6 more
wiley   +1 more source

The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis

Clinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objectives Oral dysbiosis can accelerate the progression of head and neck squamous cell carcinoma (HNSCC) by fostering a pro‐inflammatory, immunosuppressive, and metabolically altered environment. This narrative review examines the relationships between periodontitis‐associated bacteria and HNSCC, focusing on their impact on oncogenic pathways,
Yashmin Afshar, Nima Rezaei
wiley   +1 more source

Significance of serum antibodies against HPV E7, Hsp27, Hsp20 and Hp91 in Iranian HPV-exposed women

BMC Infectious Diseases, 2019
Background Among different types of human papillomavirus (HPV), types 16 and 18 were known to be high-risk agents causing mainly cervical cancer. Up to now, the potential of HPV E7 protein has been proved as a diagnostic marker of cervical cancer ...
Amitis Ramezani, Arezoo Aghakhani, Sepehr Soleymani, Anahita Bavand, Azam Bolhassani   +4 more
doaj   +1 more source

Unraveling Oral Dysbiosis: Microbial Complexity in Common Oral Diseases

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
The oral microbiome undergoes dynamic establishment from birth, maturing into a resilient ecosystem. Perturbation of this homeostasis—driven by dietary, immunological, and anatomical factors—triggers dysbiosis, which underpins the pathogenesis of major oral diseases, including dental caries, periodontal disease, salivary gland disorders, oral mucosal ...
Zixi Kang, Hong Huang, Jin Lin, Yanan Niu, Jiaxin Chen, Jiaxuan Tang, Zhengyuan Hu, Peng Liu, Jun Qu   +8 more
wiley   +1 more source

Two sides of the same coin: heat shock proteins as biomarkers and therapeutic targets for some complex diseases

Frontiers in Molecular Biosciences
Heat shock proteins are molecular chaperones that play crucial roles in the folding and unfolding of complex polypeptides within the cellular system. These molecules are involved in various processes, including vesicular transport, prevention of protein ...
Xolani Henry Makhoba
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, Volume 15, Issue 20, 27 May 2026.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

HSP27 and HSP70 expression in squamous cell carcinoma: An immunohistochemical study

Dental Research Journal, 2012
Background: Heat shock proteins (HSPs) are a family of proteins that are known to play a significant role in the repair of denatured proteins in the cell.
Parviz Deyhimi, Faezeh Azmoudeh
doaj   +1 more source