Results 31 to 40 of about 170,313 (323)

The molluscan HSP70s and their expression in hemocytes [PDF]

Invertebrate Survival Journal, 2013
The heat shock protein 70s (HSP70s) are a class of functionally related proteins involved in the folding and unfolding, translocation of other proteins, and stress responses in almost all organisms.
L Wang, C Yang, L Song
doaj   +1 more source

Membrane Fluidization Governs the Coordinated Heat-Inducible Expression of Nucleus- and Plastid Genome-Encoded Heat Shock Protein 70 Genes in the Marine Red Alga Neopyropia yezoensis

Plants, 2023
Heat shock protein 70 (HSP70) is an evolutionarily conserved protein chaperone in prokaryotic and eukaryotic organisms. This family is involved in the maintenance of physiological homeostasis by ensuring the proper folding and refolding of proteins.
Koji Mikami, Ho Viet Khoa
doaj   +1 more source

Natural autoantibodies against heat‐shock proteins hsp70 and gp96: implications for immunotherapy using heat‐shock proteins [PDF]

Immunology, 2000
SummaryImmunization of mice with cognate cancer‐derived heat‐shock protein (hsp) preparations leads to protection from cancer growth. As hsp used for vaccination or therapy are derived from autologous cancers, questions of pathological autoimmunity are of immense significance for the ongoing translation of this approach to therapy of human cancer ...
A, Ménoret, R Y, Chandawarkar, P K, Srivastava   +2 more
openaire   +2 more sources

Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1 [PDF]

, 2020
Cancer therapeutics: Extending a drug's reach A new drug that blocks heat shock proteins (HSPs), helper proteins that are co-opted by cancer cells to promote tumor growth, shows promise for cancer treatment.
Chae, Young Chan, Hong, Jun-Hee, Hu, Sung, Kang, Byoung Heon, Kim, So Yeon, Lee, Ji-Eun, Nam, Dougu, Park, Hye-Kyung, Park, Jong Bae, Yoon, Nam Gu, Yoon, Sora   +10 more
core   +1 more source

Heat Shock Protein 70 (HSP70) Induction: Chaperonotherapy for Neuroprotection after Brain Injury

Cells, 2020
The 70 kDa heat shock protein (HSP70) is a stress-inducible protein that has been shown to protect the brain from various nervous system injuries. It allows cells to withstand potentially lethal insults through its chaperone functions.
Jong Youl Kim, Sumit Barua, Meiying Huang, J. Park, M. Yenari, J. E. Lee   +5 more
semanticscholar   +1 more source

Heat Shock Proteins and Ferroptosis

Frontiers in Cell and Developmental Biology, 2022
Ferroptosis is a new form of regulatory cell death named by Dixon in 2012, which is characterized by the accumulation of lipid peroxides and iron ions. Molecular chaperones are a class of evolutionarily conserved proteins in the cytoplasm. They recognize
Ying Liu, Ying Liu, Ying Liu, Ying Liu, Lin Zhou, Lin Zhou, Lin Zhou, Lin Zhou, Yunfei Xu, Yunfei Xu, Yunfei Xu, Yunfei Xu, Kexin Li, Kexin Li, Kexin Li, Kexin Li, Yao Zhao, Yao Zhao, Yao Zhao, Yao Zhao, Haoduo Qiao, Haoduo Qiao, Haoduo Qiao, Haoduo Qiao, Qing Xu, Qing Xu, Qing Xu, Qing Xu, Jie Zhao   +28 more
doaj   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model [PDF]

, 2020
2-Methoxyestradiol is one of the natural 17β-estradiol derivatives and a potential novel anticancer agent currently being under evaluation in advanced phases of clinical trials.
Cappello F., Daca A., Gorska-Ponikowska M., Kuban-Jankowska A., Luu H. H., Marino Gammazza A., Wierzbicka J. M., Wozniak M., Zmijewski M. A.   +8 more
core   +1 more source

Developmental and hyperthermia-induced expression of the heat shock proteins HSP60 and HSP70 in tissues of the housefly Musca domestica: an in vitro study

Genetics and Molecular Biology, 2007
The expression pattern of two major chaperones, the heat shock proteins (HSPs) HSP60 and HSP70 was studied in vitro in tissues of the housefly Musca domestica during larval and adult stages of development to identify their immunological relatives and ...
Sunita Sharma, Manoj Singh Rohilla, Pramod Kumar Tiwari   +2 more
doaj   +1 more source

Membrane-anchored heat-shock protein 70 (Hsp70) in cancer

Cancer Letters, 2020
Hsp70 is a highly conserved and inducible heat shock protein that belongs to the HSP70 family of molecular chaperones and plays a central role in protein homeostasis. The main function of Hsp70 is to protect cells from physiological, pathological and environmental insults, as it assists an ATP-dependent manner the process of protein folding.
Elmallah, Mohammed I.Y., Cordonnier, Marine, Vautrot, Valentin, Chanteloup, Gaëtan, Garrido, Carmen, Gobbo, Jessica   +5 more
openaire   +6 more sources