Results 31 to 40 of about 55,389 (309)

Comparison of heat-shock responses between the hydrothermal vent shrimp Rimicaris exoculata and the related coastal shrimp Palaemonetes varians [PDF]

, 2010
The deep-sea vent shrimp Rimicaris exoculata is believed to occur at the hot end of the hydrothermal biotope in order to provide essential elements to its epibiosis. Because it is found close to hot venting water, R.
Thomas Chertemps, Sven Thatje, Shillito, Bruce, Leger, Nelly, Bruce Shillito, Nelly Léger, Chertemps, Thomas, Thatje, Sven, Ravaux, Juliette, Delphine Cottin, Cottin, Delphine, Juliette Ravaux   +11 more
core   +1 more source

Immunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme B [PDF]

, 2012
Background: We have previously reported that human recombinant granzyme B (grB) mediates apoptosis in membrane heat shock protein 70 (Hsp70)-positive tumor cells in a perforin-independent ...
Axel Walch, Alan G Pockley, Foulds, GA, Pockley, A. G., Foulds, G. A., Doss, B. T., Pockley, AG, Stangl Stefan, Kirschner, A., Foulds, G.A., Gehrmann, M., Multhoff, G., Walch Axel, Doß Brigitte T., Walch, A.K., Kirschner, A, Gehrmann Mathias, Gemma A Foulds, Stangl, S., Walch, A., Doß, B.T., Pockley, A.G., Multhoff, G, Sievert Wolfgang, Stefan Stangl, Stangl, S, Pockley Alan G., Mathias Gehrmann, Multhoff Gabriele, Sievert, W, Sievert, W., Foulds Gemma A., Andreas Kirschner, Kirschner Andreas, Wolfgang Sievert, Gehrmann, M, Gabriele Multhoff, Doß, BT, Brigitte T Doss, Walch, A   +39 more
core   +1 more source

Developmental and hyperthermia-induced expression of the heat shock proteins HSP60 and HSP70 in tissues of the housefly Musca domestica: an in vitro study

Genetics and Molecular Biology, 2007
The expression pattern of two major chaperones, the heat shock proteins (HSPs) HSP60 and HSP70 was studied in vitro in tissues of the housefly Musca domestica during larval and adult stages of development to identify their immunological relatives and ...
Sunita Sharma, Manoj Singh Rohilla, Pramod Kumar Tiwari   +2 more
doaj   +1 more source

Expression of Heat Shock Protein 70 Is Insufficient To Extend Drosophila melanogaster Longevity

G3: Genes, Genomes, Genetics, 2019
It has been known for over 20 years that Drosophila melanogaster flies with twelve additional copies of the hsp70 gene encoding the 70 kD heat shock protein lives longer after a non-lethal heat treatment.
Chengfeng Xiao, Danna Hull, Shuang Qiu, Joanna Yeung, Jie Zheng, Taylor Barwell, R. Meldrum Robertson, Laurent Seroude   +7 more
doaj   +1 more source

Heat shock protein and gene regulation in goats during heat stress

Indian Journal of Animal Sciences, 2021
Heat shock proteins (HSPs), also known as molecular chaperons are prominent stress markers. Heat shock proteins consist of highly conserved protein expressed at the time of stress, and play an important role in adaptation to the environmental stress ...
UMESH BABU CHAUDHARY, KAMENDRA SWAROOP, KHUSHBOO SETH, PRAMOD KUMAR ROUT, GURURAJ KUMARESAN   +4 more
doaj   +1 more source

Hsp70 dynamics in vivo: effect of heat shock and protein aggregation [PDF]

Journal of Cell Science, 2004
The molecular chaperone Hsp70 interacts with misfolded proteins and also accumulates in the nucleus during heat shock. Using GFP-Hsp70 and fluorescence recovery after photobleaching, we show that Hsp70 accumulates in the nucleus during heat shock not only because its inflow rate increases but also because of a marked decrease in its outflow rate ...
Xian-Chun, Zeng, Samir, Bhasin, Xufeng, Wu, Joeng-Goo, Lee, Shivani, Maffi, Christopher J, Nichols, Kyung Jin, Lee, J Paul, Taylor, Lois E, Greene, Evan, Eisenberg   +9 more
openaire   +2 more sources

Role of heat shock proteins in atrial fibrillation: From molecular mechanisms to diagnostic and therapeutic opportunities [PDF]

, 2022
Heat shock proteins (HSPs) are endogenous protective proteins and biomarkers of cell stress response, of which examples are HSP70, HSP60, HSP90, and small HSPs (HSPB).
Shao, Q., Han, X., Liu, D., Tse, G., Liu, T., Zhang, Z.   +5 more
core   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

Membrane-anchored heat-shock protein 70 (Hsp70) in cancer

Cancer Letters, 2020
Hsp70 is a highly conserved and inducible heat shock protein that belongs to the HSP70 family of molecular chaperones and plays a central role in protein homeostasis. The main function of Hsp70 is to protect cells from physiological, pathological and environmental insults, as it assists an ATP-dependent manner the process of protein folding.
Elmallah, Mohammed I.Y., Cordonnier, Marine, Vautrot, Valentin, Chanteloup, Gaëtan, Garrido, Carmen, Gobbo, Jessica   +5 more
openaire   +6 more sources

The neuroprotective potential of heat shock protein 70 (HSP70)

Molecular Medicine Today, 1999
In response to many metabolic disturbances and injuries, including stroke, neurodegenerative disease, epilepsy and trauma, the cell mounts a stress response with induction of a variety of proteins, most notably the 70-kDa heat shock protein (HSP70). Whether stress proteins are neuroprotective has been hotly debated, as these proteins might be merely an
M A, Yenari, R G, Giffard, R M, Sapolsky, G K, Steinberg   +3 more
openaire   +2 more sources