Results 71 to 80 of about 86,733 (300)

Graduate Student Literature Review: Potential use of HSP70 as an indicator of heat stress in dairy cows—A review*

Journal of Dairy Science
: Heat stress (HS) poses significant challenges to the dairy industry, resulting in reduced milk production, impaired reproductive performance, and compromised animal welfare.
M.R.H. Rakib, V. Messina, J.I. Gargiulo, N.A. Lyons, S.C. Garcia   +4 more
doaj   +1 more source

HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N6-methyladenosine. [PDF]

, 2019
Small-molecule inhibitors for the 90-kDa heat shock protein (HSP90) have been extensively exploited in preclinical studies for the therapeutic interventions of human diseases accompanied with proteotoxic stress.
Chen, Xuemei, Dai, Xiaoxia, Li, Lin, Miao, Weili, Wang, Yinsheng, Zhao, Yonghui   +5 more
core   +1 more source

XDJ1, a gene encoding a novel non-essential DnaJ homologue from Saccharomyces cerevisiae [PDF]

, 1994
The gene encoding a novel DnaJ-like protein, termed Xdj1, has been identified by amplification of Saccharomyces cerevisiae genomic DNA. An open reading frame of 1380 bp was detected. Disruption of XDJ1 did not yield any detectable new phenotype. A double-
Caplan, Avrom J., Ludwig, Gabriele, Neupert, Walter, Schwarz, Elisabeth, Westermann, Benedikt   +4 more
core   +1 more source

HEAT SHOCK PROTEIN HSP70: PREREQUISITES FOR USE AS A MEDICINAL PRODUCT

Pharmacy & Pharmacology, 2021
Heat shock protein Hsp70 is one of the main cytoprotection components under the action of various external stimuli. The analysis of the literature data shows that nowadays, the researches’ overwhelming evidence has proven the role of Hsp70 as a biological target for the drug development; however, the ideas about its use as a drug are often ...
V. M. Pokrovsky, E. A. Patrakhanov, O. V. Antsiferov, I. M. Kolesnik, A. V. Belashova, V. A. Soldatova, O. N. Pokopeiko, A. Yu. Karagodina, I. A. Arkhipov, D. G. Voronina, D. N. Sushkova   +10 more
openaire   +3 more sources

Sensing and Filtering Environmental Fluctuations: The Case of Biomolecular Condensates in Plants

Advanced Science, EarlyView.
The diversity of plant condensates reflects constraints of sessile organisms to coordinate postembryonic development with environmental adaptation. This review examines how plants employ condensates to integrate temperature, light, redox, and nutrient signals.
Panagiotis N. Moschou, Dorothee Staiger
wiley   +1 more source

Assessment of heat shock protein 70 induction by heat in alfalfa varieties and constitutive overexpression in transgenic plants. [PDF]

PLoS ONE, 2015
Heat shock proteins (HSPs) are molecular chaperones involved in many cellular functions. It has been shown that mammalian cytosolic HSP70 binds antigenic peptides mediating the activation of the immune system, and that it plays a determining role in ...
Nicoletta Ferradini, Rina Iannacone, Stefano Capomaccio, Alessandra Metelli, Nadia Armentano, Lucia Semeraro, Francesco Cellini, Fabio Veronesi, Daniele Rosellini   +8 more
doaj   +1 more source

Chromosomal location of human genes encoding major heat-shock protein HSP70 [PDF]

Somatic Cell and Molecular Genetics, 1987
The HSP70 family of heat-shock proteins constitutes the major proteins synthesized in response to elevated temperatures and other forms of stress. In eukaryotes members of the HSP70 family also include a protein similar if not identical to bovine brain uncoating ATPase and glucose-regulated proteins.
Drabkin, Harry A., Chu, Ernest H. Y., Kao, Fa -Ten, Hartz, Judith, Harrison, Gail Singer, Hart, Iris M., Wu, Barbara J., Morimoto, Richard I.   +7 more
openaire   +3 more sources

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang, Yubiao Yang, Wen Han, Yi Tang, Chengxin Yao, Fuli Zhao, Wenxiao Fang, Jinjie Li, Xiaolan Huo, Yiqian An, Yuanzhi Shao, Botao Gao, Jinchang Yin   +12 more
wiley   +1 more source

In-vivo Thermal Stress Induces Melatonin Receptors and Heat Shock Proteins Expression in the Spleen of Mice in a Time and Temperature Dependent Manner [PDF]

Journal of Stress Physiology & Biochemistry, 2023
Heat shock proteins (Hsps) responses against stress conditions. Melatonin completes its stress relieving activities via its MT1 and MT2 receptors. The present study delineates the expression pattern of Hsp70/Hsc70 and MT1/MT2 receptor proteins along with
Samik Acharjee, Shiv Shankar Singh
doaj  

Hsp70 dynamics in vivo: effect of heat shock and protein aggregation [PDF]

Journal of Cell Science, 2004
The molecular chaperone Hsp70 interacts with misfolded proteins and also accumulates in the nucleus during heat shock. Using GFP-Hsp70 and fluorescence recovery after photobleaching, we show that Hsp70 accumulates in the nucleus during heat shock not only because its inflow rate increases but also because of a marked decrease in its outflow rate ...
Xian-Chun, Zeng, Samir, Bhasin, Xufeng, Wu, Joeng-Goo, Lee, Shivani, Maffi, Christopher J, Nichols, Kyung Jin, Lee, J Paul, Taylor, Lois E, Greene, Evan, Eisenberg   +9 more
openaire   +2 more sources