Results 81 to 90 of about 50,507 (259)

Effect of extreme temperatures on powdery mildew development and Hsp70 induction in tomato and wild Solanum spp.

open access: yesPlant Protection Science, 2013
Changes in Hsp70 gene expression and protein level were studied in three Solanum spp. genotypes in response to short-term high and low temperatures and to infection by powdery mildew.
Lucie KUBIENOVÁ   +8 more
doaj   +1 more source

Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori   +9 more
wiley   +1 more source

DnaK duplication and specialization in bacteria correlates with increased proteome complexity

open access: yesmSystems
The chaperone 70 kDa heat shock protein (Hsp70) is important for cells from bacteria to humans to maintain proteostasis, and all eukaryotes and several prokaryotes encode Hsp70 paralogs.
Zhuo Pan   +4 more
doaj   +1 more source

Insulin-induced Expression of Human Heat-shock Protein Gene hsp70

open access: yesJournal of Biological Chemistry, 1989
In human hepatoma cell line Hep3B/T2, the human heat-shock-inducible gene hsp70 could be induced by insulin. The dose-dependent insulin effect correlates very well with the dissociation constant of the insulin receptor, indicating that the insulin effect is mediated by the insulin receptor. The expression of hsp70 gene was neither significantly induced
L P, Ting, C L, Tu, C K, Chou
openaire   +2 more sources

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa   +2 more
wiley   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek   +3 more
wiley   +1 more source

Production and immune response of recombinant Hsp60 and Hsp70 from the salmon pathogen Piscirickettsia salmonis

open access: yesBiological Research, 2005
We have isolated and sequenced the genes encoding the heat shock proteins 60 (Hsp60) and 70 (Hsp70) of the salmon pathogen Piscirickettsia salmonis. The sequence analysis revealed the expected two open reading frames that encode proteins with calculated ...
VIVIAN WILHELM   +5 more
doaj  

Genomic analysis, evolution and characterization of the heat shock protein-70 gene family in foxtail millet [Setaria italica (L.) P.Beauv.] along with expression analysis under saline conditions

open access: yesInternational Journal of Applied and Experimental Biology
Under stress conditions, heat shock proteins (HSPs) serve as fundamental regulators of cellular homeostasis. The molecular chaperone HSP70 belongs to a group of stress-related proteins which play important roles across growth and developmental events ...
Jawad Ali   +5 more
doaj   +1 more source

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus‐Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez   +13 more
wiley   +1 more source

Expression of Hsp70 and β-actin Genes as The Immune Response against Viral Nervous Necrosis that Infected Asian Seabass (Lates calcalifer)

open access: yesJournal of Experimental Life Science, 2018
The viral nervous necrosis (VNN) is betanodavirus of the family Nodaviridae with acute infection and associated with high levels mortality up to 100% of numerous larval-stage marine and freshwater fish species.
Yusuf Arif Wahyudi   +2 more
doaj   +1 more source

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