Results 21 to 30 of about 76,334 (253)

Expression of heat shock protein (Hsp90) paralogues is regulated by amino acids in skeletal muscle of Atlantic salmon [PDF]

, 2013
Heat shock proteins 90 (Hsp90) have an essential role in sarcomere formation and differentiation in skeletal muscle and also act as molecular chaperones during protein folding impacting a wide range of physiological processes.
Daniel Garcia de la Serrana, Johnston Ian A., Ian A. Johnston (39412), Johnston, Ian Alistair, Garcia de la serrana Daniel, Ian A Johnston, Daniel Garcia de la serrana (110372), Garcia de la Serrana Castillo, Daniel   +7 more
core   +1 more source

Effects of ultraviolet-C and microwave irradiation on the expression of heat shock protein genes in the maize weevil (Coleoptera: Curculionidae)

European Journal of Entomology, 2016
The maize weevil, Sitophilus zeamais (Motschulsky), is a major pest of stored grain kernels. Irradiation is an established technique for controlling insects in stored grain and is a major stress factor affecting these insects.
Jatuporn TUNGJITWITAYAKUL, Nujira TATUN, Boongeua VAJARASATHIRA, Sho SAKURAI   +3 more
doaj   +1 more source

Heat Shock Protein 90 (Hsp90) Expression and Breast Cancer

Pharmaceuticals, 2012
Hsp90 is an abundant protein in mammalian cells. It forms several discrete complexes, each containing distinct groups of co-chaperones that assist protein folding and refolding during stress, protein transport and degradation. It interacts with a variety
Christos A. Papadimitriou, Konstantinos Koutsoukos, Evangelos Bournakis, Flora Zagouri   +3 more
doaj   +1 more source

Spotlight on the microbes that produce heat shock protein 90-targeting antibiotics [PDF]

Open Biology, 2012
Heat shock protein 90 (Hsp90) is a promising cancer drug target as a molecular chaperone critical for stabilization and activation of several of the oncoproteins that drive cancer progression.
Peter W. Piper, Stefan H. Millson
doaj   +1 more source

The Human TPR Protein TTC4 Is a Putative Hsp90 Co-Chaperone Which Interacts with CDC6 and Shows Alterations in Transformed Cells. [PDF]

, 2008
BACKGROUND: The human TTC4 protein is a TPR (tetratricopeptide repeat) motif-containing protein. The gene was originally identified as being localized in a genomic region linked to breast cancer and subsequent studies on melanoma cell lines revealed ...
Bennett, D, Cotterill, S, Dorothy Bennett, Gilles Crevel, Bennett Dorothy, Cotterill Sue, Sue Cotterill, Crevel Gilles, Crevel, G   +8 more
core   +2 more sources

Role of heat shock in building up proteins HSP70 , HSP90, increasing anthocyanins content in callus of strawberry Fragaria ananassa Duch. [PDF]

Mesopotamia Journal of Agriculture
This study was conducted in the genetic applications laboratories of University of Mosul, College of Education for Pure Sciences. Heat shock proteins HSPs were constructed for increase of withstand long-term physical shocks, and production of resistant ...
Waad Al-Hamdani
doaj   +1 more source

MIIP inhibits clear cell renal cell carcinoma proliferation and angiogenesis via negative modulation of the HIF-2α-CYR61 axis

Cancer Biology & Medicine, 2022
Objective: In various cancers, migration and invasion inhibitory protein (MIIP) is expressed at low level and is involved in cancer pathogenesis. Herein, we sought to explore the function of MIIP in clear cell renal cell carcinoma (ccRCC). Methods: CCK-8,
Fengqi Yan, Qinhao Wang, Mingyuan Xia, Yi Ru, Wei Hu, Guang Yan, Xin Xiong, Mei Zhang, Jiancai Wang, Qi Li, Bo Zhang, He Wang, Wei Lin, Guojun Wu, Xia Li   +14 more
doaj   +1 more source

Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer

Journal of Extracellular Vesicles, 2020
Evidence has been accumulating to indicate that extracellular vesicles (EVs), including exosomes, released by cancer cells can foster tumour progression.
Kisho Ono, Chiharu Sogawa, Hotaka Kawai, Manh Tien Tran, Eman A. Taha, Yanyin Lu, May Wathone Oo, Yuka Okusha, Hirohiko Okamura, Soichiro Ibaragi, Masaharu Takigawa, Ken-Ichi Kozaki, Hitoshi Nagatsuka, Akira Sasaki, Kuniaki Okamoto, Stuart K. Calderwood, Takanori Eguchi   +16 more
doaj   +1 more source

In Vitro Inhibition of Hsp90 Protein by Benzothiazoloquinazolinequinones Is Enhanced in The Presence of Ascorbate. A Preliminary In Vivo Antiproliferative Study

Molecules, 2020
A series of benzo[g]benzothiazolo[2,3-b]quinazoline-7,12-quinones were prepared from 2-acylnaphthohydroquinones and 2-aminobenzothiazoles and were evaluated for their in vitro antiproliferative activity.
Jaime A. Valderrama, David Ríos, Giulio G. Muccioli, Pedro Buc Calderon, Julio Benites   +4 more
doaj   +1 more source

Kdm3a lysine demethylase is an Hsp90 client required for cytoskeletal rearrangements during spermatogenesis [PDF]

, 2014
The lysine demethylase Kdm3a (Jhdm2a, Jmjd1a) is required for male fertility, sex determination, and metabolic homeostasis through its nuclear role in chromatin remodeling.
Kasioulis, Ioannis, Jackson, Ian J., Botting, C. H., Botting, Catherine H., Kasioulis, I., Syred, H. M., Seawright, Anne, Fuszard, Matthew Alexander, Shirran, Sally, Van Heyningen, V., Tate, Peri, Finch, Andrew, Tate, P., Jackson, I. J., Adams, I. R., Syred, Heather M., Finch, A., Yeyati, P. L., Shaw, J., Shirran, S., Fuszard, M., Adams, Ian R., Shaw, Joseph, Seawright, A., Yeyati, Patricia L., van Heyningen, Veronica   +25 more
core   +1 more source