Results 61 to 70 of about 76,334 (253)

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Out with the old: Hsp90 finds amino acid residue more useful than co-chaperone protein [PDF]

, 2017
Redundant functions maintained from single to multi-cellular organisms have made Saccharomyces cere-visiae an important model for the analysis of con-served com-plex cellular processes. Yeast has been especially useful in understanding the regulation and
Abbey D. Zuehlke, Leonard Neckers
core   +1 more source

Molecular and morphological characterization of Avenae-group cyst nematodes (Heteroderidae) from Greece

Journal of Nematology
Cyst nematodes of the genus Heterodera comprise 87 nominal species of economically important plant parasites, with the Avenae-group one of the largest, consisting of 12 species. Samplings for cyst nematode studies were carried out from multiple locations
Skantar Andrea M., Handoo Zafar A., Hult Maria N., Habteweld Alemayehu, Kormpi Maria, Tzortzakakis Emannuel A.   +5 more
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Hsp90 is involved in apoptosis of Candida albicans by regulating the calcineurin-caspase apoptotic pathway. [PDF]

PLoS ONE, 2012
Candida albicans is the most common human fungal pathogen. Recent evidence has revealed the occurrence of apoptosis in C. albicans that is inducible by environmental stresses such as hydrogen peroxide, acetic acid, and amphotericin B.
BaoDi Dai, Yan Wang, DeDong Li, Yi Xu, RongMei Liang, LanXue Zhao, YongBing Cao, JianHui Jia, YuanYing Jiang   +8 more
doaj   +1 more source

PolyG Fibrils Coalesce Into Nuclear Ribbons That Engage Proteostasis Machinery in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong, Yongcheng Pan, Zhiyao Tang, Yuxuan Yao, Guicong Zhang, Junpu Wang, Haonan Xiao, Yun Tian, Beisha Tang, Dan Li, Qiang Guo, Ruijun Tian, Qiong Liu, Cong Liu   +13 more
wiley   +1 more source

InterAKTions with FKBPs - mutational and pharmacological exploration [PDF]

, 2013
The FK506-binding protein 51 (FKBP51) is an Hsp90-associated co-chaperone which regulates steroid receptors and kinases. In pancreatic cancer cell lines, FKBP51 was shown to recruit the phosphatase PHLPP to facilitate dephosphorylation of the kinase Akt,
Andreas März, Ricardo M Biondi, Sonja Neimanis, Anne-Katrin Fabian (383323), März, Andreas, Biondi, R., Biondi, Ricardo M., Ricardo M. Biondi (22855), Christian Kozany (26598), Kozany, Christian, Anne-Katrin Fabian, Hausch, F., Neimanis, S., Andreas März (383324), Hausch, Felix, Felix Hausch, Sonja Neimanis (383325), Christian Kozany, März, A., Kozany, C., Neimanis, Sonja, Felix Hausch (383326), Fabian, A., Fabian, Anne-Katrin   +23 more
core   +2 more sources

RNAi knockdown of heat shock proteins affects thermotolerance of Ephestia kuehniella (Lepidoptera: Pyralidae) [PDF]

Journal of Crop Protection
The Mediterranean flour moth, Ephestia kueheniella is one of the most severe pests in stores worldwide. Like many other stored product pests, chemical pesticides are often used to control this insect.
Ali Reza Bandani, Saeed Farahani
doaj   +1 more source

Virulence of HtpG⁺ and HtpG⁻ strains of Yersinia pestis for Mice and Guinea Pigs

Проблемы особо опасных инфекций, 2020
HtpG (high-temperature protein G) is a bacterial homologue of the highly conserved molecular chaperone Hsp90 of eukaryotes, which plays an important role in protection against stress in many bacterial species.
E. A. Krasil’nikova, R. Z. Shaikhutdinova, T. E. Svetoch, M. E. Platonov, T. I. Kombarova, S. A. Ivanov, S. V. Dentovskaya, A. P. Anisimov   +7 more
doaj   +1 more source

Heat-shock protein 90 promotes nuclear transport of herpes simplex virus 1 capsid protein by interacting with acetylated tubulin. [PDF]

PLoS ONE, 2014
Although it is known that inhibitors of heat shock protein 90 (Hsp90) can inhibit herpes simplex virus type 1 (HSV-1) infection, the role of Hsp90 in HSV-1 entry and the antiviral mechanisms of Hsp90 inhibitors remain unclear.
Meigong Zhong, Kai Zheng, Maoyun Chen, Yangfei Xiang, Fujun Jin, Kaiqi Ma, Xianxiu Qiu, Qiaoli Wang, Tao Peng, Kaio Kitazato, Yifei Wang   +10 more
doaj   +1 more source