Results 151 to 160 of about 3,381,955 (240)

Microbiome‐Derived Tryptophan Metabolites Regulate AhR Signaling to Restore Epithelial Barrier Integrity in Inflammatory Bowel Disease

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
The graphical abstract illustrates how microbiome‐derived indoles activate the aryl hydrocarbon receptor to restore the intestinal barrier. The picture contrasts the “leaky gut” state with the restored homeostasis achieved through AMPK, Nrf2, and IL‐22 signaling.
Mohammad Ali Mahdiabadi, Asma Moghaddam, Nafiseh Erfanian   +2 more
wiley   +1 more source

Phytochemicals as Multitarget Therapeutics in Pancreatic Cancer: Mechanisms, Clinical Evidence, and Translational Challenges

Phytotherapy Research, Volume 40, Issue 10, Page 5973-5987, October 2026.
Pancreatic cancer, particularly pancreatic ductal adenocarcinoma, is aggressive and often diagnosed late, making treatment challenging. This review highlights the potential of phytochemicals, such as curcumin and quercetin, as multitarget agents that influence key carcinogenic pathways. These compounds exhibit anticancer effects by inhibiting processes
Md. Rezaul Islam, Abdur Rauf, F. M. Shourav, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Kamala Badalova, Marcello Iriti   +7 more
wiley   +1 more source

Engineering Photothermal Nanoplatforms for Multimodal Theranostics and Biosensing

Rare Metals, Volume 45, Issue 10, October 2026.
ABSTRACT Photothermal platforms bridge materials science and biomedicine, emerging as a transformative frontier in biomedical applications. They offer spatiotemporally precise, noninvasive modalities with cell‐type‐independent efficacy for treating a range of diseases.
Xiao Han, Peng Jin, Haiqing Wang, Hao Xue   +3 more
wiley   +1 more source

Seminal Plasma Exosomal miRNA Profiling Reveals hsa‐miR‐7‐5p as a Key Regulator of Sperm Motility in Asthenozoospermia

Andrology, Volume 14, Issue 7, Page 2166-2179, October 2026.
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu, Meng‐Li Cui, Wen‐Jing Yuan, Jia‐Ning Zhang, Shuo Zhang, Xi‐Qiao Yao, Ruo‐Qing Li, Jin‐Feng Li, En‐Zhong Li   +8 more
wiley   +1 more source

Seminal Extracellular Vesicles as Molecular Modulators of Male Reproductive Function

Reproduction in Domestic Animals, Volume 61, Issue S3, October 2026.
ABSTRACT Extracellular vesicles (sEVs) contained in seminal plasma (SP) maintain, in concert with free SP‐components (proteins, hormones, cytokines, metabolites and antioxidants) under an endocrine umbrella the functional in vivo homeostasis of ejaculated spermatozoa. The sEVs define a generic mixture of nanovesicles delivered by male epithelial cells,
Heriberto Rodriguez‐Martinez, Jordi Roca, Fernando Peña Vega, Emilio A. Martinez   +3 more
wiley   +1 more source

Heat Shock Proteins in Cancer: Mechanisms and Therapeutic Targeting. [PDF]

MedComm (2020)
Ma S, Liu CQ, Ma SY, Wang SG, Xia QD, Xu MY.   +5 more
europepmc   +1 more source

Heat shock proteins in male infertility: recent advances and clinical implications. [PDF]

Front Cell Dev Biol
Wu Z, Zhang W, Han R, Ping H, Xia L, Ding H, Yuan J, Wang X, Qin Q.   +8 more
europepmc   +1 more source

More than the 'master regulator of cytosolic proteostasis': new roles for HSF1 in promoting tissue health. [PDF]

Philos Trans R Soc Lond B Biol Sci
Labbadia J.
europepmc   +1 more source

Molecular characterization and seasonal, sex-associated expression patterns of HSP genes in Eurygaster integriceps (Hemiptera: Scutelleridae). [PDF]

J Insect Sci
Abdollahi F, Amiri A, Bandani AR.
europepmc   +1 more source

Proteostasis and ageing dissidence. [PDF]

Philos Trans R Soc Lond B Biol Sci
Babu N, Whalen K, Freeman B.
europepmc   +1 more source