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Heat shock protein HSP90 and its association with the cytoskeleton: a morphological study

Biochemistry and Cell Biology, 1992
To investigate the cellular localization of the 90-kilodalton heat shock protein (HSP90) and its interaction with the cytoskeleton, we performed single- and double-staining immunofluorescence microscopy of cytoskeletal proteins and HSP90 in the absence and presence of cytoskeletal inhibitors. As a model, we used a human endometrial adenocarcinoma cell
Y, Fostinis   +3 more
openaire   +2 more sources

Prognostic Significance of Heat Shock Proteins HSP70 and HSP90 in Endometrial Carcinomas

Cancer Detection <html_ent glyph="@amp;" ascii="&amp;"/> Prevention, 1998
Heat shock proteins HSP70 and HSP90 are sex steroid receptor-associated proteins, and HSP90 expression has reportedly been correlated with sex steroid receptor status in endometrial carcinomas. HSP70 is also known to associate with several oncogene products such as p53 protein, and expression of HSP70 has been reported to be a prognostic factor in ...
K, Nanbu   +6 more
openaire   +2 more sources

Allosteric Modulators of Heat Shock Protein 90 (HSP90)

2016
Heat shock proteins (HSP) are a family of molecular chaperones that are the most conserved proteins present in both prokaryotes and eukaryotes. HSPs facilitate numerous events in cellular physiology including: protein recycling, transportation, migration, post-translational modification, and the regulation of signalling pathways.
Yen Chin Koay, Shelli McAlpine
openaire   +1 more source

Heat Shock Protein 90 (Hsp90) in Fungal Growth and Pathogenesis

Current Fungal Infection Reports, 2014
Invasive fungal infections, such as invasive candidiasis and invasive aspergillosis, have an important impact on morbidity and mortality in intensive care unit (ICU), cancer, and transplant patient populations. New therapies are required to overcome the limitations of the current antifungal armamentarium and the emergence of resistance.
Frédéric Lamoth   +2 more
openaire   +1 more source

The role and therapeutic potential of Hsp90, Hsp70, and smaller heat shock proteins in peripheral and central neuropathies

Medicinal Research Reviews, 2021
Subhabrata Chaudhury   +2 more
exaly  

Participation of Hsp70 and Hsp90α Heat Shock Proteins in Stress Response in the Course of Type 1 Diabetes Mellitus

Doklady Biological Sciences, 2020
E G Novoselova   +2 more
exaly  

Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach

International Journal of Molecular Sciences, 2017
Suman Chatterjee, Timothy Burns
exaly  

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