Results 221 to 230 of about 59,353 (250)
Some of the next articles are maybe not open access.
The glucose-regulated protein grp94 is related to heat shock protein hsp90
Journal of Molecular Biology, 1987We report the sequence of a cDNA clone that encodes the C-terminal half of the hamster 94 X 10(3) Mr glucose-regulated protein, grp94. The amino acid sequence of this protein is about 50% homologous to Drosophila hsp83 and yeast hsp90, suggesting that grp94 and hsp90 have similar functional properties.
P K, Sorger, H R, Pelham
openaire +2 more sources
Developmental Genetics, 1993
AbstractWe have isolated two genes from Zea mays encoding proteins of 82 and 81 kD that are highly homologous to the Drosophila 83‐kD heat shock protein gene and have analyzed the structure and pattern of expression of these two genes during heat shock and development.
K A, Marrs +6 more
openaire +2 more sources
AbstractWe have isolated two genes from Zea mays encoding proteins of 82 and 81 kD that are highly homologous to the Drosophila 83‐kD heat shock protein gene and have analyzed the structure and pattern of expression of these two genes during heat shock and development.
K A, Marrs +6 more
openaire +2 more sources
Allosteric Modulators of Heat Shock Protein 90 (HSP90)
2016Heat shock proteins (HSP) are a family of molecular chaperones that are the most conserved proteins present in both prokaryotes and eukaryotes. HSPs facilitate numerous events in cellular physiology including: protein recycling, transportation, migration, post-translational modification, and the regulation of signalling pathways.
Yen Chin Koay, Shelli McAlpine
openaire +1 more source
Heat Shock Protein 90 (Hsp90) in Fungal Growth and Pathogenesis
Current Fungal Infection Reports, 2014Invasive fungal infections, such as invasive candidiasis and invasive aspergillosis, have an important impact on morbidity and mortality in intensive care unit (ICU), cancer, and transplant patient populations. New therapies are required to overcome the limitations of the current antifungal armamentarium and the emergence of resistance.
Frédéric Lamoth +2 more
openaire +1 more source
Prognostic Significance of Heat Shock Proteins HSP70 and HSP90 in Endometrial Carcinomas
Cancer Detection <html_ent glyph="@amp;" ascii="&"/> Prevention, 1998Heat shock proteins HSP70 and HSP90 are sex steroid receptor-associated proteins, and HSP90 expression has reportedly been correlated with sex steroid receptor status in endometrial carcinomas. HSP70 is also known to associate with several oncogene products such as p53 protein, and expression of HSP70 has been reported to be a prognostic factor in ...
K, Nanbu +6 more
openaire +2 more sources
Molecular modelling and docking studies on heat shock protein 90 (Hsp90) inhibitors
SAR and QSAR in Environmental Research, 2010An adenosine tri-phosphate (ATP)-dependent molecular chaperone heat shock protein (Hsp90) is of current interest as a potential anticancer drug target. It has several oncogenic client proteins involved in signal transduction, cell cycle regulation and apoptosis.
A K, Saxena, S, Saxena, S S, Chaudhaery
openaire +2 more sources
Heat shock proteins HSP90, HSP70 and GRP78 expression in medullary thyroid carcinoma
Annals of Diagnostic Pathology, 2017Medullary thyroid carcinoma management consists mainly of surgical resection and is largely chemoresistant. There is ongoing effort to discover novel therapies for medullary thyroid carcinoma. Increased levels of heat shock proteins have been associated with multiple cancers and are being studied as potential therapeutic targets.
Ethan, Soudry +5 more
openaire +2 more sources
Heat shock factors: integrators of cell stress, development and lifespan
Nature Reviews Molecular Cell Biology, 2010Richard I Morimoto, Lea Sistonen
exaly
Regulation of heat shock transcription factors and their roles in physiology and disease
Nature Reviews Molecular Cell Biology, 2017Rocio Gomez-Pastor, Dennis J Thiele
exaly
Role of the Major Heat Shock Proteins as Molecular Chaperones
Annual Review of Cell Biology, 1993C Georgopoulos
exaly