Results 141 to 150 of about 83,455 (287)

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

Journal of Internal Medicine, EarlyView.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron, Jennifer S. Lin, Mark I. Ryder, Peter Bergman   +3 more
wiley   +1 more source

HSV-1 as a Potential Driver of Alzheimer's Disease. [PDF]

Pathogens
Li DY, Choi ES, Bao X.
europepmc   +1 more source

<b>MUTATION OF THE THYMIDINE KINASE GENE IN A GANCICLOVIRRESISTANT STRAIN OF HERPES SIMPLEX VIRUS TYPE 1 (HSV-1) DETECTED BY PCR-SSCP AND PCR-DIRECT SEQUENCIN</b><b>G </b>

, 1996
Hiroshi Shiota, Eiji Kudo, Yasuo Mimura, Mitsuo Itakura   +3 more
openalex   +2 more sources

Characteristics of Acyclovir‐Resistant Herpes Simplex Virus Infection in Hematological Patients

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objective Acyclovir‐resistant herpes simplex virus infections pose a significant challenge in immunosuppressed patients. This study aimed to characterize the clinical features, treatment outcomes, and mortality associated with acyclovir‐resistant herpes simplex virus infection. Materials and Methods A retrospective analysis was conducted on 18
Reema Shehadeh, Mor Bar Ilan, Sara Dovrat, Ronit Yerushalmi, Michal Tepperberg Oikawa, Evangelia Piperi, Nikolaos G. Nikitakis, Noam Yarom   +7 more
wiley   +1 more source

FLARE: A Flow Cytometry-Based Fluorescent Assay for Measuring HSV-1 Nuclear Egress. [PDF]

Bio Protoc
Dai B, Polack L, Moores S, Calderon-Zavala AC, Heldwein EE.   +4 more
europepmc   +1 more source

PRIMARY INFECTION BY HSV-1 IN PEDIATRIC PATIENTS: A CASE REPORT

, 2018
Lígia Anholeti Cardoso, Inarei José Paulini Júnior, Regina Célia de Souza Campos Fernandes   +2 more
openalex   +1 more source

Figure S7 from Safety and Efficacy of Intraventricular Immunovirotherapy with Oncolytic HSV-1 for CNS Cancers

, 2023
Kyung‐Don Kang, Joshua D. Bernstock, Stacie K. Totsch, Sam E. Gary, Abbey Rocco, Li Nan, Rong Li, Tina Etminan, Xiaosi Han, Elizabeth A. Beierle, Tanja Eisemann, Robert J. Wechsler‐Reya, Sejong Bae, Richard J. Whitley, G. Yancey Gillespie, James M. Markert, Gregory K. Friedman   +16 more
openalex   +1 more source

Herpesvirus Simplex Virus‐1 Exploits Inflammation to Infect Periodontal Stem Cells and Disrupt Lineage Commitment

Journal of Periodontal Research, EarlyView.
HSV‐1 infects oral mesenchymal stem cells both in vitro and in vivo to dysregulate their lineage commitment. An inflamed gingival environment increases susceptibility to HSV‐1 infection, which further elevates proinflammatory cytokine levels and exacerbates alveolar bone loss.
Araceli Valverde, Raza Ali Naqvi, Yinghua Chen, Alireza Moshaverinia, Anne George, Deepak Shukla, Gloria Martinez, Gabriella Chapa, Salvador Nares, Afsar R. Naqvi   +9 more
wiley   +1 more source

HSV-1 US3: A Master Mimic Hijacking Host Kinase Networks for Viral Dominance. [PDF]

J Med Virol
Hossain I, Nelson CJ, Dutta O, Mohan H, Hasan M, Kousoulas KG.   +5 more
europepmc   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source