Results 101 to 110 of about 112,416,099 (307)

Use of acyclovir for suppression of human immunodeficiency virus infection is not associated with genotypic evidence of herpes simplex virus type 2 resistance to acyclovir: analysis of specimens from three phase III trials.

, 2010
Herpes simplex virus type 2 (HSV-2) is the most common cause of genital ulcer disease and is a cofactor for HIV-1 acquisition and transmission. We analyzed specimens from three separate phase III trials of acyclovir (ACV) for prevention of HIV-1 ...
Kathy Baisley, Clare Tanton, Anna Wald, Rula Green Gladden, Connie Celum, Changalucha, John, Weiss, Helen A, David M. Koelle, Watson-Jones, Deborah, Jairam Lingappa, Helen A. Weiss, Richard J. Hayes, John Changalucha, Celum, Connie, Tanton, Clare, Hayes, Richard J, Deborah Watson-Jones, Gladden, Rula Green, Baisley, Kathy, Koelle, David M, Marshak, Joshua O, Wald, Anna, Lingappa, Jairam, Joshua O. Marshak   +23 more
core   +1 more source

Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus. [PDF]

, 2007
BACKGROUND: Epidemiologic data suggest that infection with herpes simplex virus type 2 (HSV-2) is associated with increased genital shedding of human immunodeficiency virus type 1 (HIV-1) RNA and HIV-1 transmissibility. METHODS: We conducted a randomized,
Becquart, Pierre, Van de Perre, Philippe, Sanon, Anselme, Segondy, Michel, Weiss, Helen A, Andonaba, Jean-Baptiste, Vallo, Roselyne, ANRS 1285 Study Group, Sawadogo, Adrien, Nagot, Nicolas, Foulongne, Vincent, Vergne, Laurence, Mayaud, Philippe, Ouédraogo, Abdoulaye, Defer, Marie-Christine, Djagbaré, Didier, Konaté, Issouf   +16 more
core   +1 more source

A case series of necrotizing periodontal diseases in hospitalized patients: What hasn't been said yet?

Clinical Advances in Periodontics, EarlyView.
Abstract Background Necrotizing periodontal diseases (NPDs) are uncommon and severe inflammatory conditions characterized by tissue necrosis, painful ulceration, and rapid clinical progression, frequently associated with systemic immunosuppression. Limited data exist regarding their clinical presentation and management in hospital settings.
Osmaria Letthycia Carvalho Leal, Fernanda Bortolotto, Mariana Cristina Manoel, Gabriela Silveira de Araújo, Ana Carolina Fragoso Motta, Leandro Dorigan de Macedo, Lara Maria Alencar Ramos Innocentini, Joab Cabral Ramos, Isabel Schausltz Pereira Faustino   +8 more
wiley   +1 more source

Evaluation of a prototype biplex VIDAS immunoassay for type-specific detection of HSV-1 and HSV-2 IgG antibodies

Journal of Clinical Microbiology
Type-specific serologic detection of IgG antibodies to herpes simplex virus (HSV)-1 and HSV-2 provides important diagnostic and epidemiological information.
Marie Roccon, Hardy Charly, Aurélie Truffot, Laurent Pelletier, Patrice Morand, Olivier Epaulard, Raphaële Germi, Julien Lupo   +7 more
doaj   +1 more source

Antiviral activity of compound 2 on Vero cell line infected with HSV-1, HSV-2 with serum and HSV-2 acyclovir resistant strains.

, 2018
Antiviral activity of compound 2 on Vero cell line infected with HSV-1, HSV-2 with serum and HSV-2 acyclovir resistant strains.
Roberto Ferrarese (234640), Giulio Poli (809754), Claudio Zamperini (1316742), Cristina Tintori (1478107), David Lembo (467396), Elisa Rita Ceresola (5043545), Elena Dreassi (1316751), Filippo Canducci (145970), Maurizio Botta (103410), Annalaura Brai (1478116), Valeria Cagno (1779763), Giulia Iovenitti (4254919)   +11 more
core   +1 more source

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source

Mathematics of HSV-2 Dynamics

, 2010
The thesis is based on using dynamical systems theories and techniques to study the qualitative dynamics of herpes simplex virus type 2 (HSV-2), a sexually-transmitted disease of major public health significance. A deterministic model for the interaction of the virus with the immune system in the body of an infected individual (in vivo) is designed ...
openaire   +2 more sources

HSV-1 glycoproteins do not interact with HCMV glycoproteins.

, 2016
(A) ARPE-19 cells were transduced with Ad vectors expressing Ad-tet-trans alone (tet, as a negative control), HSV-1 gH/gL, or HSV-1 gH/gL along with HCMV gB (as indicated along the top of the panel).
Paul W. Howard (3173379), Todd W. Wisner (307889), David C. Johnson (307895), Adam L. Vanarsdall (307887)   +3 more
core   +1 more source

Creating Social Value Through Innovation: The Roles of Social Innovation Orientation, Frugal Innovation, and Reverse Engineering

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Despite growing scholarly interest in social innovation, limited research explains how and under what conditions social innovation orientation is associated with corporate social performance. This study develops and tests a moderated mediation model in which frugal innovation is proposed to transmit the association between enacted social ...
Khanh Huy Nguyen, Mai Dong Tran, Samuel Adomako   +2 more
wiley   +1 more source

Image_4_HSV-2-Specific Human Female Reproductive Tract Tissue Resident Memory T Cells Recognize Diverse HSV Antigens.tiff

, 2022
Antigen-specific TRM persist and protect against skin or female reproductive tract (FRT) HSV infection. As the pathogenesis of HSV differs between humans and model organisms, we focus on humans with well-characterized recurrent genital HSV-2 infection ...
Christine Johnston (375038), David M. Koelle (8138436), Jia Zhu (135506), Lei Jin (120473), Anna Wald (172640), Dana Varon (12324485), Lichun Dong (466119), Christine M. Posavad (12324488), Lawrence Corey (140058), Meei-Li Huang (342097), Lichen Jing (446155), Stacy Selke (363785), Kerry J. Laing (8138433)   +12 more
core   +1 more source