Results 131 to 140 of about 112,416,099 (307)

Detection, quantification and genotyping of Herpes Simplex Virus in cervicovaginal secretions by real-time PCR: a cross sectional survey

Virology Journal, 2005
Background Herpes Simplex Virus (HSV) Genital Ulcer Disease (GUD) is an important public health problem, whose interaction with HIV results in mutually enhancing epidemics. Conventional methods for detecting HSV tend to be slow and insensitive.
Natividad-Sancho Angels, Bailey Robin L, Aryee Esther AN, Kaye Steve, Holland Martin J   +4 more
doaj   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

HSV-2 Suppression and the Incidence of HIV [PDF]

New England Journal of Medicine, 2008
Lisco, Andrea, Vanpouille, Christophe
openaire   +2 more sources

Analysis of individualized brain–gut association networks and transcriptional patterns in major depressive disorder

Interdisciplinary Medicine, EarlyView.
Individualized brain–gut association networks suggest potential neuropathological mechanisms in MDD and MDDSI. Multilevel brain–gut association changes involving HSV‐1 and inflammation may be relevant to MDD, whereas alterations related to insulin metabolism may play a potential role in the neuropathological mechanisms of MDDSI.
Wei Wang, Baoyuan Zhu, Yuanyuan Huang, Liqin Liang, Zhaobo Li, Yunheng Diao, Minxin Guo, Heng Zhang, Jing Zhou, Fengchun Wu, Kai Wu   +10 more
wiley   +1 more source

A Semi‐Automated Microfluidic Platform Employing Machine Learning Analysis to Study Adhesion Kinetics in Acute Myeloid Leukemia

Microscopy Research and Technique, EarlyView.
We have developed a semi‐automated shear flow platform using bright‐field optics and a machine‐learning analysis algorithm to dissect tumor‐microenvironment interactions. The algorithm quantifies the extent of adhesion at the single‐cell level and delivers consistent results within minutes instead of hours, facilitating high‐throughput analysis ...
Driti Ashok, Dennis Raith, Gabriel Kalweit, Maria Kalweit, Anusha Klett, Justus Duyster, Jonas Bermeitinger, Tanja Nicole Hartmann   +7 more
wiley   +1 more source

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti‐tumor necrosis factor alpha therapy in children

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is ...
Jonathan E. M. O'Donnell, Carlie Bolles, Claire R. Reilly, Manal Morgan, Christopher Burgess, Fariha Balouch, Peter J. Lewindon   +6 more
wiley   +1 more source

Cytokine secretion patterns distinguish herpes simplex virus type 2 meningitis from herpes simplex virus type 2 genital herpes

Frontiers in Immunology
The aim of this study was to identify immune factors that distinguish patients with herpes simplex virus type 2 (HSV-2) meningitis from patients with HSV-2 genital herpes by analyzing demographic data, in vitro production of cytokines and other immune ...
Moa Bjerhem, Alexandra Svensson, Alexandra Svensson, Marie Studahl, Marie Studahl, Petra Tunbäck, Petra Tunbäck, Eva-Marie Boman, Kenny Brandström, Christine Lingblom, Christine Lingblom, Azadeh Reyahi, Karolina Thörn, Kristina Eriksson, Kristina Eriksson   +14 more
doaj   +1 more source

Image‐based and biochemical multimodal phenotyping for explainable classification of chia (Salvia hispanica L.) genotypes

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND This study developed an explainable machine learning framework integrating morphological, color, and biochemical characteristics for classifying chia (Salvia hispanica L.) genotypes. A dataset was assembled from 1200 seed images spanning four genotypes, from which 17 morphological and color features were extracted.
Sevim Akcura, Irem Poyraz, Beyza Ciftci, Mahmut Kaplan   +3 more
wiley   +1 more source

Seroepidemiology of Herpes Simplex Viruses Type 1 and 2 in Pregnant Women in Croatia

Medicina
Background and Objectives: Herpes simplex viruses (HSV-1 and HSV-2) are one of the most widespread causes of human viral infections. In Croatia, only two published studies have analyzed the seroprevalence of HSV infections in childbearing-aged and ...
Tatjana Vilibic-Cavlek, Marko Belamaric, Thomas Ferenc, Dan Navolan, Branko Kolaric, Ljiljana Milasincic, Ljiljana Antolasic, Mateja Vujica Ferenc, Maja Vilibic, Adriana Lukunic, Maja Bogdanic   +10 more
doaj   +1 more source