Results 151 to 160 of about 80,157 (261)

Distinct NK Cell Genetic Variants Are Associated With HSV-2 Versus VZV Infection of the CNS. [PDF]

open access: yesJ Med Virol
Graninger M   +4 more
europepmc   +1 more source

The impact of frailty on glycaemic control in older adults with type 1 diabetes: An observational study

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims The type 1 diabetes population is ageing. Frailty is the age‐related physiological decline that occurs across organ systems, increasing the body's vulnerability to stressors. Current consensus‐based guidelines, derived from evidence in type 2 diabetes, prioritise hypoglycaemia avoidance, which increases falls, hospitalisation and ...
Jonathan A. Golding   +5 more
wiley   +1 more source

Role of human RNase 7 in neuronal and glial cell models: moving towards an unexpected new functional link

open access: yesThe FEBS Journal, EarlyView.
Human RNase 7 is known to exert antimicrobial activity in epithelial tissues. Here, using SH‐SY5Y and U‐87 MG, neuroblastoma and glioblastoma cell lines, respectively, we found that RNase 7 enhances immune responses to LPS stimulation by reducing the expression of pro‐inflammatory cytokines, nitric oxide, and ROS.
Rosanna Culurciello   +9 more
wiley   +1 more source

1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

open access: yesThe FEBS Journal, EarlyView.
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah   +5 more
wiley   +1 more source

A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2. [PDF]

open access: yesNature
Vollmer B   +9 more
europepmc   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

open access: yesThe FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju   +2 more
wiley   +1 more source

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