Results 171 to 180 of about 17,745,525 (306)

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Oncolytic Vaccinia Virus‐HSP70‐shRNA Amplifies Viral Replication, ROS/Autophagy, and Immunity to Fight Colorectal Cancer

Cancer Science, EarlyView.
OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan, Ruikang Liu, Fangying Shao, Zheqi Cai, Yingfei Fang, Kan Chen, Yanrong Zhou, Ting Ye, Gongchu Li   +8 more
wiley   +1 more source

Association of CMV, HSV-2, and HPV infections with spontaneous abortion. [PDF]

AJOG Glob Rep
Pirani MD, Ravanshad M, Shayestehpour M, Mousavi SA, Jahanabadi S.   +4 more
europepmc   +1 more source

Triple‐Mutated HSV‐1 Expressing Soluble B7‐1 Plus CTLA‐4 Blockade Suppresses Lymph Node Metastasis in Tongue Cancer

Cancer Science, EarlyView.
In murine tongue cancer models, T‐mB7‐1, a triple‐mutated oncolytic herpes simplex virus type 1 (HSV‐1) engineered to express soluble B7‐1, suppresses cervical lymph node metastasis and improves survival, addressing a major prognostic determinant in oral squamous cell carcinoma (OSCC).
Akinari Sugauchi, Toshihiro Uchihashi, Hirotaka Ito, Miwako Iwai, Yuzuri Tsurumaki Sato, Kyoko Kurioka, Sena Zeynep Usta, Minoru Tanaka, Mikihiko Kogo, Susumu Tanaka, Hiroshi Fukuhara, Tomoki Todo   +11 more
wiley   +1 more source

Risk of HSV-2 Acquisition Among Women with Bacterial Vaginosis: Systematic Review and Meta-Analysis. [PDF]

Viruses
Whitt TN, Heath A, Hill DJ, Brubaker DK, Farr Zuend C.   +4 more
europepmc   +1 more source

Image‐Based Spatio‐Temporal Interpolation for Split Rendering

Computer Graphics Forum, EarlyView.
Abstract Low‐powered devices – such as small form factor head‐mounted displays (HMDs) – struggle to deliver a smooth and high‐quality viewing experience, due to their limited power and rendering capabilities. Cloud rendering attempts to solve the quality issue, but leads to prohibitive latency and bandwidth requirements, hindering use with HMDs over ...
M. Steiner, T. Köhler, L. Radl, B. Budge, M. Steinberger   +4 more
wiley   +1 more source

Comparison of the Accuracy of HSV1 and HSV2 Antibody Tests with PCR in the Diagnosis of Recurrent Genital Herpes

Clinical, Cosmetic and Investigational Dermatology
Jia Deng, Yu-Jian Ye, Qiu-Ping Chen, Yi-Jin Zhang, Ji-Feng Liu Department of Dermatology, Hangzhou Third People’s Hospital, Hangzhou, People’s Republic of ChinaCorrespondence: Ji-Feng Liu, Department of Dermatology, Hangzhou Third People’s Hospital, No ...
Deng J, Ye YJ, Chen QP, Zhang YJ, Liu JF
doaj  

Preclinical evaluation of high-dose Griffithsin carrageenan fast-dissolving insert for HIV, HSV-2, and HPV prevention. [PDF]

Microbiol Spectr
Fernández Romero JA, Barnable P, Visciano ML, Aravantinou M, Meyer A, Grecky S, Schiro F, Grasperge B, Gadsden J, Kommineni N, Angsantikul P, Kumar N, Nuttall J, Haddad LB, Teleshova N.   +14 more
europepmc   +1 more source

Edge‐preserving noise for diffusion models

Computer Graphics Forum, EarlyView.
Abstract Classical diffusion models typically rely on isotropic Gaussian noise, treating all regions uniformly and overlooking structural information important for high‐quality generation. We introduce an edge‐preserving diffusion process that generalizes isotropic models via a hybrid noise scheme with an edge‐aware scheduler that smoothly transitions ...
Jente Vandersanden, Sascha Holl, Xingchang Huang, Gurprit Singh   +3 more
wiley   +1 more source

Expression of concern: HSV-2 regulates monocyte inflammatory response via the Fas/FasL pathway. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source