Results 91 to 100 of about 117,409 (314)
Purification and concentration of model viruses using single‐pass tangential flow filtration
Biotechnology Progress, EarlyView.Single‐pass TFF was developed for an enveloped and non‐enveloped virus for use in continuous downstream purification processes. Enveloped virus was concentrated and purified. Abstract The vaccine and viral vector industry is growing at an accelerated rate.
Luis Alberto Mejía‐Manzano +6 more
wiley +1 more source
HSV-1 envelope proteins and their roles in entry and membrane fusion.
, 2019 (A) HSV-1 entry into cells requires the coordinated efforts of the receptor-binding glycoprotein gD (RCSB PDB: 2C36), the heterodimer gH/gL (RCSB PDB: 3M1C), and the fusogen gB (RCSB PDB: 5V2S).
Ekaterina E. Heldwein (815959) +1 more
core +1 more source
Risk factors for herpes simplex virus type 2 and HIV among women at high risk in northwestern Tanzania: preparing for an HSV-2 intervention trial. [PDF]
, 2007 OBJECTIVES: To determine prevalence of and risk factors for herpes simplex virus type 2 (HSV-2) and HIV among women being screened for a randomized, controlled trial of HSV suppressive therapy in northwestern Tanzania. METHODS: Two thousand seven hundred
Mugeye, Kokugonza +10 more
core +1 more source
Status and future of recombinant adeno‐associated virus vector manufacturing
Biotechnology Progress, EarlyView.Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
Clinical Advances in Periodontics, EarlyView.Abstract Background Necrotizing periodontal diseases (NPDs) are uncommon and severe inflammatory conditions characterized by tissue necrosis, painful ulceration, and rapid clinical progression, frequently associated with systemic immunosuppression. Limited data exist regarding their clinical presentation and management in hospital settings.
Osmaria Letthycia Carvalho Leal +8 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.4′‐ThioRNA was broadly tolerated across multiple positions in SARS‐CoV‐2‐targeting siRNAs, but full 4'‐thio modification of both strands caused a reduction in RNAi activity. Sense‐strand segmentation improved RNAi and antiviral activity, particularly when the nick was located at position 10 from the 5′‐end of the sense strand, thereby unlocking the ...
Yuhei Nogi +5 more
wiley +1 more source
, 2019 <p>Since the genome of herpes simplex virus 1 (HSV-1) was first sequenced more than 30 years ago, its predicted 80 genes have been intensively studied.
Florian Erhard (184910) +3 more
core +1 more source
Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation
Annals of the Child Neurology Society, EarlyView.ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed +5 more
wiley +1 more source
HSV-2 infection dynamics from multiple model simulations.
, 2018 (A) Total quantity of HSV-2 within the simulation region at all time points throughout year long simulations. (B) Total percentage of tissue damage within the simulation region at all time points throughout year long simulations.
Catherine M. Byrne (5147228) +2 more
core +1 more source
ChemSusChem, Volume 18, Issue 6, March 15, 2025.This study presents a symmetric supercapacitor with activated carbon electrodes and a “water‐in‐salt” electrolyte (WiSE) based on lithium perchlorate, offering over 100,000 cycles with over 90 % capacity retention. The supercapacitor operates efficiently from −20 to 80 °C, enhancing performance, stability, and all‐season operability.
Zahid Ali Zafar +5 more
wiley +1 more source