Results 151 to 160 of about 177,583 (277)

1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

The FEBS Journal, EarlyView.
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah, Grace Filbertine, Lucy Gill, Asangaedem Akpan, Marie M. Phelan, Helen Louise Wright   +5 more
wiley   +1 more source

Editorial: Oncolytic virotherapy

Frontiers in Molecular Biosciences, 2023
Ahmed Majeed Al-Shammari, Pier Paolo Piccaluga, Pier Paolo Piccaluga   +2 more
doaj   +1 more source

Restriction of HSV-1 replication by Pistacia vera L. extracts reveals a promising strategy for regulating virus-mediated chemokine response in monocytic cells. [PDF]

Sci Rep
Pennisi R, Costa M, Tamburello MP, Trischitta P, Mandalari G, Sciortino MT.   +5 more
europepmc   +1 more source

Chronic ulcerative oesophagitis rich in IgG4‐positive plasma cells – a distinct clinicopathological entity

Histopathology, EarlyView.
We report a series of 12 patients (mean age 63 years) with chronic oesophageal ulceration showing morphological features of IgG4‐related inflammatory disease. Most patients underwent several rounds of endoscopy until this association was recognized. The majority of patients went into clinical and histological remission following corticosteroid therapy.
Hanna Henzinger, Ian Brown, Anthony J Gill, Tomas Slavik, Giuseppe Zamboni, Cord Langner   +5 more
wiley   +1 more source

Host Immune Response Mechanisms Against Herpes Simplex Virus Type 2 Infection. [PDF]

Pathogens
Mei Y, Teng H, Wang J.
europepmc   +1 more source

Auto‐inducible expression of chimeric antigen receptor T cells using the NR4A1 promoter

Immunology &Cell Biology, EarlyView.
The NR4A1 promoter is a compact auto‐inducible promoter to drive CAR expression in T cells. Compared with EF1α, or existing synthetic antigen‐inducible promoters, NR4A1 is more compact and ensures that resting CAR T cells express reduced baseline CAR. NR4A1 allows rapid induction upon antigen encounter with reduced T‐cell exhaustion.
Samuel WJ Smith‐Bell, Joshua C Halpin, Phillip K Darcy, Thiloma Liyanage, Lachlan J Dobson, Alexander D McLellan   +5 more
wiley   +1 more source

Actin and Rho GTPases in herpesvirus biology [PDF]

, 2007
ENQUIST, LW, Favoreel, Herman, FEIERBACH, B   +2 more
core   +1 more source

Neuroinflammation as a result of non‐neurotropic herpesvirus infection

Immunology &Cell Biology, EarlyView.
Atypical memory B cells (ABCs) might stimulate autoreactive T cells to cause neuroinflammation and CNS myeloid cell activation during MS. Abstract The non‐neurotropic Epstein Barr virus (EBV) has been suggested to initiate the prodromal phase of multiple sclerosis (MS), often years before the first clinical symptoms. This review discusses mechanisms by
Christian Münz
wiley   +1 more source

Herpes simplex virus type 2 encephalitis in critically ill adults: A retrospective analysis of EURECA and Herpetics cohort studies. [PDF]

Crit Care
Volpé T, Hassold N, de Montmollin E, Dupuis C, Sarton B, Guidet B, Bruneel F, Sazio C, Chabanne R, Brulé N, El Kalioubie A, Alves M, Tadié JM, Citerio G, Helbok R, Horn J, Demeret S, Bailly P, Frérou A, Ben Hadj Salem O, Engrand N, da Silva D, Timsit JF, Sonneville R, Jaquet P, ENCEPHALITICA, EURECA study groups.   +26 more
europepmc   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source