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HSV shedding

Antiviral Research, 2004
Viral shedding of HSV occurs frequently in infected individuals. HSV is shed asymptomatically from multiple anatomical sites and shedding, like exposure, is a significant risk for transmission. However, the relationship between shedding frequency, viral titer and transmission is unknown. HSV-2 shedding is affected by the site and time since acquisition
S L, Sacks   +10 more
openaire   +2 more sources

HSV-2 transmission

Antiviral Research, 2004
A number of important risk factors for the acquisition of HSV-2 have been established including female gender, black or Hispanic ethnic origin, HIV infection, age, and increased number of sexual partners. Transmission is influenced by a number of biological factors such as sexual behavior, use of condoms, duration of relationships, and knowledge of a ...
S L, Sacks   +10 more
openaire   +2 more sources

HSV: immunopathological aspects of HSV infection

2007
Introduction “What is food to one man is bitter poison to others” Lucretius De Rerum Natura (50BCE) Foreign material entering multicellular organisms triggers a range of defense reactions which, when successful, subjugates and removes the invaders.
Kaustuv Banerjee, Barry T. Rouse
openaire   +1 more source

HSV Mutagenesis

2003
Herpes genomes are large and complex, with many interactions among herpes encoded proteins, herpes DNA and RNA, and the host cell. These interactions begin as the virus enters the cell, and continue as the decision for latency or lytic replication is made.
openaire   +2 more sources

Seroprevalence of HSV-1 and HSV-2 in Barbados

Medical Microbiology and Immunology, 2004
Type-specific enzyme-linked immunosorbent assays, based upon recombinant glycoprotein G (gG), were used to detect antibodies to HSV-1 and HSV-2, in a small Caribbean island population. A blinded serosurvey was performed on samples from 184 blood donors, 122 pregnant women, and 120 HIV-positive patients. The seroprevalence of HSV-1 and HSV-2 was 81% and
openaire   +2 more sources

Herpes Simples (HSV-1 e HSV-2)

Este capítulo trata sobre a Herpes Simples (HSV-1 e HSV-2), apresentando sua etiologia, fisiopatologia, manifestações clínicas, diagnóstico, tratamento e prognóstico. A condição é explicada em seus aspectos principais, incluindo fatores de risco e mecanismos de desenvolvimento.
Amanda Caroline Bogo Piccinin   +7 more
openaire   +1 more source

Targeting HSV amplicon vectors

Methods, 2004
Several techniques have been developed to deliver DNA directly into mammalian cells, spanning in difficulty from simple mixing procedures to complex systems requiring expensive equipment. Viral vectors have proven able to deliver genes into mammalian cells with high efficiency and low toxicity.
GRANDI, Paola   +3 more
openaire   +2 more sources

Oncolytic Virotherapy by HSV

2018
Oncolytic virotherapy is a kind of antitumor therapy using viruses with natural or engineered tumor-selective replication to intentionally infect and kill tumor cells. An early clinical trial has been performed in the 1950s using wild-type and non-engineered in vitro-passaged virus strains and vaccine strains (first generation oncolytic viruses ...
Daisuke, Watanabe, Fumi, Goshima
openaire   +2 more sources

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