Results 71 to 80 of about 191,153 (333)
Regulation of HSV Transcription.
Herpes simplex virus (HSV) transcripts share many features with both cellular mRNA and the mRNAs expressed by other nuclear-replicating DNA viruses: they are capped, polyadenylated, and generally have an approximately 150 base leader between the cap and translation initiation codon.
openaire +2 more sources
HSV Cheats the Executioner [PDF]
In this issue of Cell Host & Microbe, Huang et al. (2015) and Guo et al. (2015), along with recent work by Wang et al. (2014), reveal that HSV ribonucleotide reductase has opposing activities in either inducing or preventing necroptosis, depending on the host species.
Mossman, Karen L., Weller, Sandra K.
openaire +2 more sources
Characterization of the Interaction between the Herpes Simplex Virus Type I Fc Receptor and Immunoglobulin G [PDF]
Herpes simplex virus type I (HSV-1) virions and HSV-1-infected cells bind to human immunoglobulin G (hIgG) via its Fc region. A complex of two surface glycoproteins encoded by HSV-1, gE and gI, is responsible for Fc binding.
Bjorkman, Pamela J. +5 more
core +1 more source
Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang +10 more
wiley +1 more source
Automated Ripeness Detection of Oil Palm Fruit Using a Hybrid GLCM-HSV-KNN Model
Accurately determining the ripeness of oil palm fruit is crucial for ensuring the quality of palm oil. However, traditional manual methods are often time-consuming and less accurate.
Mirfan +3 more
doaj +1 more source
Hyperferritinemic sepsis: an opportunity for earlier diagnosis and intervention?
We describe a case of an infant with HSV meningitis and septic shock who demonstrated a remarkably high serum ferritin level. Aggressive pediatric intensive care and the administration of high dose glucocorticoids were not able to reverse the multiple ...
E. Scott Halstead +3 more
doaj +1 more source
Herpes simplex keratitis: Challenges in diagnosis and clinical management [PDF]
Herpes simplex virus is responsible for numerous ocular diseases, the most common of which is herpetic stromal keratitis. This is a recurrent infection of the cornea that typically begins with a subclinical infection of the cornea that establishes a ...
Azher, Tayaba N +4 more
core +3 more sources
EGR Proteins Mediate Interferon‐Independent Anti‐HSV‐1 Responses Through Viral and Host Targets
Early antiviral responses are typically mediated by interferons. However, during HSV‐1 infection, host early growth response (Egr) genes, which are not interferon‐stimulated genes, are quickly induced by viral protein ICP0. EGR proteins, in turn, suppress viral lytic infection by activating viral latency‐associated (LAT) and host immune regulatory ...
Shuaishuai Wang +4 more
wiley +1 more source
In cases where man-made fishing nets are forgotten or lost underwater, these nets are called ghost nets. These ghost nets threaten the underwater ecosystem over time and reduce the biodiversity of living creatures underwater. For this reason, studies are
Gülşah Karaduman +2 more
doaj +1 more source
Visualization of DNA G-quadruplexes in herpes simplex virus 1-infected cells [PDF]
We have previously shown that clusters of guanine quadruplex (G4) structures can form in the human herpes simplex-1 (HSV-1) genome. Here we used immunofluorescence and immune-electron microscopy with a G4-specific monoclonal antibody to visualize G4 ...
Artusi, Sara +6 more
core +1 more source

