Results 101 to 110 of about 24,253,245 (291)
Impact of host immunity on HTLV-1 pathogenesis: potential of Tax-targeted immunotherapy against ATL
Retrovirology, 2019 Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other inflammatory diseases.
M. Kannagi +4 more
semanticscholar +1 more source
HTLV-1 bZIP factor gene: Its roles in HTLV-1 pathogenesis [PDF]
Molecular Aspects of Medicine, 2010 The HTLV-1 bZIP factor (HBZ) gene is transcribed as an anti-sense transcript of HTLV-1 from the 3' long terminal repeat (LTR). Recent studies showed that the HBZ gene was expressed in all ATL cases, suggesting its critical role in leukemogenesis. In addition, only the HBZ gene sequence remains intact, unaffected by nonsense mutations and deletion.
openaire +2 more sources
Perceptions of donor screening—Do I always need to tell the truth?
Transfusion Medicine, EarlyView.Abstract Background The Donor Health Assessment Questionnaire (DHQ) is fundamental to blood safety. We describe attitudes towards truthfulness among first‐time donors who tested positive for transfusion transmissible infections and those who did not.
Sheila F. O'Brien +2 more
wiley +1 more source
Absence of HTLV-1/2 infection and dermatological diseases in Manaus, State of Amazonas, Brazil
Revista da Sociedade Brasileira de Medicina Tropical, 2014 Introduction The prevalence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) infection is heterogeneous across different populations. We tested the hypothesis that HTLV-1/2 infection occurs more often in dermatological patients.
Leny Nascimento da Motta Passos +6 more
doaj +1 more source
Epidemiological analysis of HTLV-1 and HTLV-2 infection among different population in Central China. [PDF]
PLoS ONE, 2013 BACKGROUND: HTLV-1 and HTLV-2 are retroviruses linked etiologically to various human diseases, and both of them can be transmitted by vertical route, sexual intercourse, blood transfusion and intravenous drug use.
Yunyun Ma +9 more
doaj +1 more source
Human T-lymphotropic virus and transfusion safety. Does one size fit all? [PDF]
, 2015 Human T-cell leukemia viruses (HTLV-1 and HTLV-2) are associated with a variety of human diseases, including some severe ones. Transfusion transmission of HTLV through cellular blood components is undeniable.
Catalano, Liviana +7 more
core +1 more source
bioRxiv, 2019 The human T cell leukemia virus HTLV-1 establishes a persistent infection in vivo in which the viral sense-strand transcription is usually silent at a given time in each cell.
Michi Miura +5 more
semanticscholar +1 more source
HTLV-1 and Innate Immunity [PDF]
Viruses, 2011 Innate immunity plays a critical role in the host response to a viral infection. The innate response has two main functions. First, it triggers effector mechanisms that restrict the infection. Second, it primes development of the adaptive response, which completes the elimination of the pathogen or of infected cells.
Chloé Journo, Renaud Mahieux
openaire +3 more sources
International Journal of Cancer, Volume 158, Issue 6, Page 1528-1540, 15 March 2026.What's new? Adult T‐cell leukemia/lymphoma (ATL) is a rare and aggressive malignancy caused by human T‐cell leukemia virus type 1 (HTLV‐1). The authors comprehensively analyzed the epidemiological and clinical features of ATL over a 30‐year period in French Guiana, a region with high HTLV‐1 endemicity and a multiethnic population.
Jill‐Léa Ramassamy +16 more
wiley +1 more source