Results 81 to 90 of about 24,253,245 (291)

Antiretroviral Therapy in HTLV-1 Infection: An Updated Overview

Pathogens, 2020
The human T cell leukemic/lymphotropic virus type 1 (HTLV-1), discovered several years ago, is the causative agent for a rapid progressive haematological malignancy, adult T cell leukemia (ATL), for debilitating neurological diseases and for a number of ...
Francesca Marino-Merlo, E. Balestrieri, C. Matteucci, A. Mastino, S. Grelli, B. Macchi   +5 more
semanticscholar   +1 more source

Human Milk Practices in Swedish Neonatal Units: Results From a Nationwide Survey

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to describe the routines for handling mother's own milk and donor human milk in Swedish neonatal care units related to national guidelines. Methods A web‐based survey of 24 of 38 neonatal units and 19 of 28 human milk banks in Sweden. Results Despite national guidelines, breast milk handling varied widely.
Ylva Thernström Blomqvist, Anna‐My Lund, Fredrik Ahlsson, Jenny Ericson, Charlotta Karlsson, Josefin Lundström, Ingela Sandström, Anna Gustafsson   +7 more
wiley   +1 more source

Prevalence of Human T-lymphotropic virus type 1 and 2 among blood donors in Manaus, Amazonas State, Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 2017
Introduction: Human T-lymphotropic virus type 1 and 2 (HTLV-1/2) is endemic in Brazil, but few studies have investigated the seroprevalence of HTLV and its subtypes among blood donors in the capital city Manaus, Amazonas State, Brazil.
Márcia Poinho EncarnaçÃo de Morais, Cynara Melo Gato, Lucinei Alves Maciel, Pritesh Lalwani, Cristóvão Alves Costa, Jaila Dias Borges Lalwani   +5 more
doaj   +1 more source

Substitution of HIV type 1 Nef with HTLV-1 p12 [PDF]

, 2004
Human retroviruses, such as HTLV-1 and HIV-1, encode accessory proteins, which regulate viral pathogenesis. The p12 protein of HTLV-1 is encoded from the pX-I open reading frame, and is critical for efficient virus replication in rabbits.
Ratner, Lee, Tsukahara, Tomonori
core   +2 more sources

Detection of clinical and neurological signs in apparently asymptomatic HTLV-1 infected carriers: Association with high proviral load

PLoS Neglected Tropical Diseases, 2019
Several studies suggest that HTLV-1 infection may be associated with a wider spectrum of neurologic manifestations that do not meet diagnostic criteria for HAM/TSP.
Michel E. J. Haziot, M. R. Gascón, Tatiane Assone, L. A. Fonseca, Olinda, do Carmo Luiz, J. Smid, A. Paiva, R. Marcusso, C. A., Penalva de Oliveira, Jorge, CassebID   +12 more
semanticscholar   +1 more source

Clinical features and incidence of central nervous system involvement in patients with adult T‐cell leukaemia/lymphoma

British Journal of Haematology, EarlyView.
Summary Central nervous system (CNS) involvement is a known complication of adult T‐cell leukaemia/lymphoma (ATL), but its clinical characteristics and incidence still remain unclear. This study characterized the clinical features and incidence of CNS involvement in patients with ATL (CNS‐ATL).
Takuya Ueno, Makoto Yoshimitsu, Momone Sameshima, Taichi Nagano, Rika Akahoshi, Yusetsu Takeshita, Aya Shodai, Kodai Shima, Naosuke Arima, Yuhei Kamada, Daisuke Nakamura, Kenji Ishitsuka   +11 more
wiley   +1 more source

Inhibition of Tunneling Nanotube (TNT) Formation and Human T-cell Leukemia Virus Type 1 (HTLV-1) Transmission by Cytarabine

Scientific Reports, 2018
The human T-cell leukemia virus type 1 (HTLV-1) is highly dependent on cell-to-cell interaction for transmission and productive infection. Cell-to-cell interactions through the virological synapse, biofilm-like structures and cellular conduits have been ...
M. Omsland, C. Pise-Masison, Dai Fujikawa, V. Galli, C. Fenizia, R. W. Parks, B. Gjertsen, G. Franchini, V. Andresen   +8 more
semanticscholar   +1 more source

The Role of Chemokines in the Pathogenesis of HTLV-1

Frontiers in Microbiology, 2020
Human T cell leukemia virus type 1 (HTLV-1) is a human retrovirus that is associated with two main diseases: HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T cell leukemia/lymphoma (ATL).
Razieh Zargari, Maryam Mahdifar, A. Mohammadi, Z. Vahidi, G. Hassanshahi, H. Rafatpanah   +5 more
semanticscholar   +1 more source

Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation

The FEBS Journal, EarlyView.
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley   +1 more source

HTLV-1 Proliferation after CD8+ Cell Depletion by Monoclonal Anti-CD8 Antibody Administration in Latently HTLV-1-Infected Cynomolgus Macaques

Microbiology Spectrum, 2023
Human T-cell leukemia virus type 1 (HTLV-1) induces chronic asymptomatic latent infection with a substantial proviral load but without significant viral replication in vivo.
Midori Nakamura-Hoshi, Takushi Nomura, Masako Nishizawa, Trang Thi Thu Hau, Hiroyuki Yamamoto, Midori Okazaki, Hiroshi Ishii, Kenzo Yonemitsu, Yuriko Suzaki, Yasushi Ami, Tetsuro Matano   +10 more
doaj   +1 more source