Results 21 to 30 of about 33,805 (209)
HTLV-2 Enhances CD8+ T Cell-Mediated HIV-1 Inhibition and Reduces HIV-1 Integrated Proviral Load in People Living with HIV-1. [PDF]
Viruses, 2022 Abad-Fernández M +10 more
europepmc +3 more sources
Estimating the number of HTLV-2 infected persons in the world [PDF]
Retrovirology, 2015 The number of HTLV-1 infected persons in the world has recently been estimated to be at least at 5 to 10 million or perhaps higher due to unavailable data (Gessain and Cassar Front Microbiol 2012). We decided to undertake a similar estimation for HTLV-2 infection. A targeted review of the literature revealed HTLV-2 prevalence estimates in blood donors (
Edward L. Murphy +2 more
openalex +3 more sources
HTLV-2 Encoded Antisense Protein APH-2 Suppresses HIV-1 Replication. [PDF]
Viruses, 2021 Antisense protein of Human T-cell Leukemia Virus Type 2 (HTLV-2), also called APH-2, negatively regulates the HTLV-2 and helps the virus to maintain latency via scheming the transcription. Despite the remarkable occurrence of HTLV-2/HIV-1 co-infection, the role of APH-2 influencing HIV-1 replication kinetics is poorly understood and needs investigation.
Londhe R, Kulkarni S.
europepmc +5 more sources
Novel perspectives on antisense transcription in HIV-1, HTLV-1, and HTLV-2. [PDF]
Front Microbiol, 2022 The genome of retroviruses contains two promoter elements (called long terminal repeat or LTR) at the 5′ and 3′ end of their genome. Although the expression of retroviral genes generally depends on the promoter located in the 5′ LTR, the 3′ LTR also has promoter activity responsible for producing antisense transcripts.
Lin E, Panfil AR, Sandel G, Jain P.
europepmc +4 more sources
Neurological Aspects of HIV-1/HTLV-1 and HIV-1/HTLV-2 Coinfection. [PDF]
Pathogens, 2020 Simultaneous infection by human immunodeficiency viruses (HIV) and human T-lymphotropic viruses (HTLV) are not uncommon since they have similar means of transmission and are simultaneously endemic in many populations. Besides causing severe immune dysfunction, these viruses are neuropathogenic and can cause neurological diseases through direct and ...
Araujo AQ.
europepmc +5 more sources
Anti-HTLV-1/2 IgG Antibodies in the Breastmilk of Seropositive Mothers
Microorganisms, 2021 Background: HTLV-1/2 mother-to-child transmission (MTCT) is an important route for the maintenance of HTLV-1/2 within populations and disproportionally contributes to the burden of HTLV-1-associated diseases.
Carolina Rosadas +4 more
doaj +1 more source
HTLV-1 and HTLV-2 infections significantly alter small RNA expression in asymptomatic carriers. [PDF]
Front Med (Lausanne)IntroductionThis study investigates the impact of HTLV-2 infection on small RNA (sRNA) expression profiles, building on previous findings related to HTLV-1.MethodsUsing Illumina Massive Parallel Sequencing, we analyzed sRNA profiles from asymptomatic HTLV-1 and HTLV-2 infected individuals and healthy controls.ResultsOur results reveal significant ...
Fernandes LA +9 more
europepmc +4 more sources
Silencers of HTLV-1 and HTLV-2: the pX-encoded latency-maintenance factors. [PDF]
Retrovirology, 2019 Of the members of the primate T cell lymphotropic virus (PTLV) family, only the human T-cell leukemia virus type-1 (HTLV-1) causes disease in humans-as the etiological agent of adult T-cell leukemia/lymphoma (ATLL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other auto-inflammatory disorders.
Harrod R.
europepmc +5 more sources
Infectio, 2020 Background: Infection with the Human T-cell lymphotropic virus (HTLV) type 1 and 2 is endemic in South America. There are only a few clinical reports of this retrovirus in patients in Ecuador, without employing virus-isolation methods or viral DNA ...
Carmen Mosquera
doaj +1 more source
Frontiers in Public Health, 2023 IntroductionMigratory flows play a significant role in the spread of human T-lymphotropic virus 1/2 (HTLV-1/2). In the last decade, a substantial migration of individuals occurred from Haiti and Venezuela to Brazil.
Thaís Augusto Marinho +9 more
doaj +1 more source