CXCR3/CXCL10 Axis-Mediated T Cell Infiltration in the Lungs of Patients With HTLV-1-Associated Diseases: Implications for Subclinical Pulmonary Involvement. [PDF]
Abstract HTLV‐1 is a retrovirus associated with adult T cell leukemia/lymphoma (ATL) and inflammatory diseases, including HTLV‐1‐associated myelopathy (HAM) and HTLV‐1‐associated bronchopneumonopathy (HAB). Although pulmonary complications are common in HTLV‐1‐associated diseases, the underlying mechanisms remain unclear.
Tsuchimoto K +8 more
europepmc +2 more sources
Diagnostic utility and pitfalls of human T-lymphotropic virus serology in adult T-cell leukemia/lymphoma: evidence from a 25-year pathology-based nonendemic cohort. [PDF]
Abstract Adult T‐cell leukemia/lymphoma (ATLL) is a distinct type of peripheral T‐cell lymphoma (PTCL) driven by human T‐lymphotropic virus type I (HTLV‐1)–infected T cells, but diagnosis can be confounded by histological overlap with non‐ATLL PTCL. While molecular testing is the diagnostic gold standard in endemic areas, HTLV‐1/2 serology is often ...
Yuan CT +10 more
europepmc +2 more sources
HTLV-1 Tax-1 interacts with SNX27 to regulate cellular localization of the HTLV-1 receptor molecule, GLUT1 [PDF]
An estimated 10–20 million people worldwide are infected with human T cell leukemia virus type 1 (HTLV-1), with endemic areas of infection in Japan, Australia, the Caribbean, and Africa.
Al-Saleem, Jacob +6 more
core +3 more sources
Background. Human T-cell lymphotropic virus type 1 (HTLV-1) is responsible for tropical spastic paraparesis and HTLV-1-associated leukemia/lymphoma. The infection is endemic in some areas of Peru, but its prevalence in the Peruvian Amazon is not well ...
José-Manuel Ramos-Rincón +10 more
doaj +1 more source
Loss of correlation between HIV viral load and CD4+ T-cell counts in HIV/HTLV-1 co-infection in treatment naive Mozambican patients [PDF]
Seven hundred and four HIV-1/2-positive, antiretroviral therapy (ART) naïve patients were screened for HTLV-1 infection. Antibodies to HTLV-1 were found in 32/704 (4.5%) of the patients.
Augusto, O +7 more
core +2 more sources
Serum- and/or- cerebrospinal fluid (CSF) samples obtained from 190 patients suffering from chronic, progressive neurological disease were screened for the presence of human T-cell lymphotropic viruses type I (HTLV-I) and type II (HTLV-II) antibodies over
Olinda Macêdo +5 more
doaj +1 more source
Detection of HIV-1 infection in dried blood spots from a 12-year-old ABO bedside test card [PDF]
Background and Objectives: We tested dried blood from an ABO bedside test card which had been stored at room temperature for 12 years, to prove that a patient with HIV-1 infection had been infected by blood transfusion. Materials and Methods: Immunoblots
Eberle, J. +4 more
core +1 more source
Introduction: Human T Cell Lymphotrophic virus (HTLV) is endemic in many regions of the world including Nigeria but not ubiquitous. It has been shown to be causally associated with T cell leukaemia and other myelopathies.
Babatunde Olusola +4 more
doaj +1 more source
Background HTLV-I is the causal agent of adult T cell leukemia (ATLL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Biomarkers are needed to diagnose and/or predict patients who are at risk for HAM/TSP or ATLL.
Mahieux Renaud +10 more
doaj +1 more source
Chronic adult T-cell Leukemia in a young male after blood transfusion as a newborn [PDF]
Human T-cell Lymphotropic virus type 1 (HTLV-1) is the etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL) and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HTM/TSP).
Altube, Alejandra +10 more
core +2 more sources

