Results 61 to 70 of about 26,474 (270)
Testing problems in diagnosing human T-lymphotropic virus (HTLV) infection, mostly HTLV-II, have been documented in HIV/AIDS patients. Since December 1998, the Immunology Department of Instituto Adolfo Lutz (IAL) offers HTLV-I/II serology to Public ...
Fabrício Jacob +3 more
doaj +1 more source
Translation inhibition by rocaglates is independent of eIF4E phosphorylation status [PDF]
Rocaglates are natural products that inhibit protein synthesis in eukaryotes and exhibit antineoplastic activity. In vitro biochemical assays, affinity chromatography experiments coupled with mass spectrometry analysis, and in vivo genetic screens have ...
Cencic, Regina +4 more
core +1 more source
Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro +6 more
wiley +1 more source
Sexual transmission of human T-cell lymphotropic virus type 1 [PDF]
Human T-cell lymphotropic virus type 1 (HTLV-1) is endemic in many parts of the world and is primarily transmitted through sexual intercourse or from mother to child.
Casseb, Jorge Simão do Rosário +1 more
core +1 more source
Along with peptides, MHC polymorphisms allosterically tune peptide energy landscapes, altering conformational dynamics and T cell receptor recognition. This dynamic allostery mechanism explains how subtle polymorphic differences drive differential immune specificity across individuals and populations.
Bassant Eldaly, Brian M. Baker
wiley +1 more source
Inflammatory myopathy on HTLV-I infection: case report [PDF]
We describe a 41 years old woman who 17 years ago presented hypotonia and proximal muscular weakness in the upper and lower limbs. On neurological examination, the biceps, triceps and Achilles reflexes were absent; the brachioradialis reflexes were ...
Rosana Herminia Scola +5 more
doaj +1 more source
Abstract This study aims to explore the mechanism of action of the Bromodomain‐containing protein 4 (BRD4) inhibitor GNE‐987 in the treatment of pediatric T‐cell Acute Lymphoblastic Leukemia (T‐ALL), focusing on its effect in inhibiting T‐ALL cell proliferation by activating the HLA Complex P5 (HCP5) Super‐enhancer.
Xu Sang +6 more
wiley +1 more source
Intrathecal synthesis of human T-lymphotropic virus type 1 (HTLV-1) antibodies (Abs) represents conclusive evidence of a specific immune response in the central nervous system of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP ...
Luiz Claudio Pereira Ribeiro +4 more
doaj +1 more source
Transcriptional activation of immediate-early gene ETR101 by human T-cell leukaemia virus type I Tax [PDF]
Human T-cell leukaemia virus type I (HTLV-I) Tax regulates viral and cellular gene expression through interactions with multiple cellular transcription pathways.
Chen, L +9 more
core +1 more source
Helminths as architects of trained tolerance: implications for human health
Abstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Quinn Moroz +2 more
wiley +1 more source

