Results 21 to 30 of about 19,818 (181)

Prevalence and Risk Factors for HTLV-1/2 Infection in Quilombo Remnant Communities Living in the Brazilian Amazon

Frontiers in Public Health, 2022
Human T-lymphotropic viruses 1 and 2 (HTLV-1 and HTLV-2) are retroviruses that originated on the African continent and dispersed throughout other continents through human migratory flows. This study describes the prevalence of HTLV-1 and HTLV-2 infection
Wandrey Roberto dos Santos Brito, Wandrey Roberto dos Santos Brito, Greice de Lemos Cardoso-Costa, Greice de Lemos Cardoso-Costa, Lourival Marques Roland Junior, Lourival Marques Roland Junior, Keise Adrielle Santos Pereira, Keise Adrielle Santos Pereira, Felipe Teixeira Lopes, Felipe Teixeira Lopes, Bernardo Cintra dos Santos, Aline Cecy Rocha de Lima, Aline Cecy Rocha de Lima, Isabella Nogueira Abreu, Isabella Nogueira Abreu, Carlos Neandro Cordeiro Lima, Carlos Neandro Cordeiro Lima, Sandra Souza Lima, Izaura M. Vieira Cayres Vallinoto, Izaura M. Vieira Cayres Vallinoto, Eduardo José Melo dos Santos, Eduardo José Melo dos Santos, João Farias Guerreiro, Antonio Carlos Rosário Vallinoto, Antonio Carlos Rosário Vallinoto   +24 more
doaj   +1 more source

Global stability of a general HTLV-I infection model with Cytotoxic T-Lymphocyte immune response and mitotic transmission

Alexandria Engineering Journal, 2023
Mathematical models have been considered as a robust tool to support biological and medical studies of human viral infections. The global stability of viral infection models remains an important and largely open research problem.
A.M. Elaiw, A.S. Shflot, A.D. Hobiny
doaj   +1 more source

Human T-lymphotropic virus 1/2 infection among immigrants and refugees in Central Brazil, an emerging vulnerable population

Frontiers in Public Health, 2023
IntroductionMigratory flows play a significant role in the spread of human T-lymphotropic virus 1/2 (HTLV-1/2). In the last decade, a substantial migration of individuals occurred from Haiti and Venezuela to Brazil.
Thaís Augusto Marinho, Larissa Silva Magalhães, Kamila Cardoso dos Santos, Thaynara Lorrane Silva Martins, Grazielle Rosa da Costa e Silva, Ágabo Macedo da Costa e Silva, Megmar Aparecida dos Santos Carneiro, Karlla Antonieta Amorim Caetano, Sheila Araújo Teles, Regina Maria Bringel Martins   +9 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Extracellular Vesicles in HTLV-1 Communication: The Story of an Invisible Messenger

Viruses, 2020
Human T-cell lymphotropic virus type 1 (HTLV-1) infects 5–10 million people worldwide and is the causative agent of adult T-cell leukemia/lymphoma (ATLL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) as well as other ...
Sarah Al Sharif, Daniel O. Pinto, Gifty A. Mensah, Fatemeh Dehbandi, Pooja Khatkar, Yuriy Kim, Heather Branscome, Fatah Kashanchi   +7 more
doaj   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Prevalence of HTLV-I and HTLV-II infections among HIV-1-infected asymptomatic individuals in São Paulo, Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 1997
Human immunodeficiency virus (HIV-1)-infected subjects with acquired immunodeficiency syndrome (AIDS) are often infected with multiple pathogens. In particular, HTLV-I and HTLV-II infections have been found more frequently in AIDS patients than in ...
Jorge CASSEB, Adele CATERINO-DE ARAUJO, Marisa A. HONG, Simone SALOMÃO, Dana GALLO, R. Michael HENDRY, Alberto J.S. DUARTE   +6 more
doaj   +1 more source

Glycoengineered Recombinant Alpha1‐Antitrypsin Results in Comparable In Vitro and In Vivo Activities to Human Plasma‐Derived Protein

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Alpha‐1‐antitrypsin (A1AT) is a multifunctional, clinically important, high‐value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes, graft‐versus‐host disease, cystic fibrosis, and various viral infections. Currently, the only U.S. food and drug administration‐approved treatment for
Frances Rocamora, Chen‐Lin Hsieh, Sanne Schoffelen, Johnny Arnsdorf, Eric A. Toth, Abdul S. Yunus, Thomas E. Cleveland IV, Sara Petersen Bjørn, Mina Ying Min Wu, Noel G. McElvaney, Bjørn Gunnar Rude Voldborg, Thomas R. Fuerst, Nathan E. Lewis   +12 more
wiley   +1 more source

A novel high-performance rapid screening test for the detection of total HTLV-I and HTLV-II antibodies in HTLV-I/II infected patients

BMC Infectious Diseases
Rapid diagnosis of human T-cell lymphotropic virus (HTLV) type-I and -II infections are essential for timely and cost-effective disease interventions.
Lay Sin Teoh, Vincent Guiraud, Haris Ong, Yang Du, Zhihai Zhao, Agnès Gautheret-Dejean, Na Xu   +6 more
doaj   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source