Results 81 to 90 of about 4,651,731 (290)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

The Clarens web services architecture [PDF]

, 2003
Clarens is a uniquely flexible web services infrastructure providing a unified access protocol to a diverse set of functions useful to the HEP community. It uses the standard HTTP protocol combined with application layer, certificate based authentication
Aslakson, Eric, Bunn, Julian J., Newman, Harvey B., Steenberg, Conrad D., Thomas, Michael, van Lingen, Frank   +5 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Three-Basis Loop-Back QKD: A Passive Architecture for Secure and Scalable Quantum Mobile Networks

Entropy
The Loop-Back Quantum Key Distribution (LB-QKD) protocol establishes a bidirectional architecture in which a single photon travels forth and back through the same optical channel.
Luis Adrián Lizama-Pérez, Patricia Morales-Calvo   +1 more
doaj   +1 more source

Comparative analysis of HTTP request handling in different Python frameworks [PDF]

MATEC Web of Conferences
The Hypertext Transfer Protocol (HTTP) has become a fundamental component for client-server communication in web applications. This paper investigates the performance and suitability of HTTP request handling in three popular Python frameworks: Flask ...
Malatjie Patrick Given, Faniso-Myaka Zimbini   +1 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

SPDY vs HTTP/1.1: An Empirical Evaluation of Network Protocol Performance [PDF]

, 2014
As the Internet evolves, the reduction of page load time has an increased importance. Additionally, the application layer is an ideal place to change as it avoids altering existing implementations.
Chambers, Stephen Matthew
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Optimization of Remote Intake Pump Control System Using MQTT Protocol Based on PLCnext (Case Study : Pluit Reservoir)

Jurnal Jaringan Telekomunikasi
This research was motivated by operational inefficiencies in the intake pump control system at Pluit Reservoir, caused by the 1.4 km distance between the Water Treatment Plant (WTP) and the pump house, as well as the failure of a previous fiber optic ...
Fransisxus Wisnu Pranoto
doaj   +1 more source

Nonsurgical Strategies in Patients With NET Liver Metastases: A Protocol of Four Systematic Reviews

JMIR Research Protocols, 2014
BackgroundPatients diagnosed with neuroendocrine tumors (NETs) with hepatic metastases generally have a worse prognosis as compared with patients with nonmetastasized NETs.
Limani, Perparim, Tschuor, Christoph, Gort, Laura, Balmer, Bettina, Gu, Alexander, Ceresa, Christos, Raptis, Dimitri Aristotle, Lesurtel, Mickael, Puhan, Milo, Breitenstein, Stefan   +9 more
doaj   +1 more source