Results 151 to 160 of about 12,981,558 (250)

A Re-examination of Epistemological Paradigms Describing Animal Behavior in 8 Points. ‘Animal Consciousness and Science Matter’: a Reply

Relations, 2013
Roberto Marchesini
doaj   +1 more source

Zoonotic Transmission of Soil-Transmitted Helminths in a Setting with Close Human-Animal Interaction: A Cross-Sectional Pilot Study from Meghalaya, India. [PDF]

Am J Trop Med Hyg
Mawrie UG, Manuel M, Marbaniang PJ, Sangriang IL, Laxmanan S, Ajjampur SSR, Sarkar R.   +6 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Exploring the Human-Animal Interaction (HAI) for Children with ASD Across Countries: A Systematic Review. [PDF]

J Autism Dev Disord
Chan HW, Hsu LSJ, Shum KKM.
europepmc   +1 more source

Human-Animal Interaction Research: Progress and Possibilities. [PDF]

Front Psychol, 2019
Griffin JA, Hurley K, McCune S.
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Human Animal Interaction and Interaction Involvement

, 2011
With increasing use of animals for therapeutic intervention, learning assistance, and health promotion, it becomes increasingly important to understand potential outcomes.
Rawson, Kim M.
core  

Editorial: Evidencing the impact of human-animal interaction for those living with mental health problems. [PDF]

Front Psychiatry
Shoesmith E, Hawkins RD, Ratschen E.
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Effects of human-animal interaction on salivary and urinary oxytocin in children and dogs. [PDF]

Psychoneuroendocrinology
Gnanadesikan GE, King KM, Carranza E, Flyer AC, Ossello G, Smith PG, Steklis NG, Steklis HD, Carter CS, Connelly JJ, Barnett M, Gee N, Tecot SR, MacLean EL.   +13 more
europepmc   +1 more source