Results 161 to 170 of about 1,230,484 (264)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Expanding human animal interaction research; is human animal interaction associated with psychological functioning?

, 2017
The purpose of the current study was to expand the current Human Animal interaction research by broadening the range of individuals included in this research area; as well as examining the association between human animal interaction and elements of ...
O'Neill, Kelly
core  

Zoonotic Transmission of Soil-Transmitted Helminths in a Setting with Close Human-Animal Interaction: A Cross-Sectional Pilot Study from Meghalaya, India. [PDF]

Am J Trop Med Hyg
Mawrie UG, Manuel M, Marbaniang PJ, Sangriang IL, Laxmanan S, Ajjampur SSR, Sarkar R.   +6 more
europepmc   +1 more source

Human-Animal Interaction Research: Progress and Possibilities. [PDF]

Front Psychol, 2019
Griffin JA, Hurley K, McCune S.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Editorial: Evidencing the impact of human-animal interaction for those living with mental health problems. [PDF]

Front Psychiatry
Shoesmith E, Hawkins RD, Ratschen E.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Effects of human-animal interaction on salivary and urinary oxytocin in children and dogs. [PDF]

Psychoneuroendocrinology
Gnanadesikan GE, King KM, Carranza E, Flyer AC, Ossello G, Smith PG, Steklis NG, Steklis HD, Carter CS, Connelly JJ, Barnett M, Gee N, Tecot SR, MacLean EL.   +13 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Human-animal interaction and One Health: establishment and validation of the Brazilian version of the Animal Empathy Scale. [PDF]

Einstein (Sao Paulo)
Savieto RM, Oliveira LPG, Borba GB, Victor EDS, Bomfim SB, de Oliveira LB, Catissi G, Patrício KP, Kiriyama EJ, Leão ER.   +9 more
europepmc   +1 more source