Results 101 to 110 of about 13,632,971 (306)

Reviewing and extending the five-user assumption: A grounded procedure for interaction evaluation [PDF]

, 2013
" © ACM, 2013. This is the author's version of the work. It is posted here by permission of ACM for your personal use. Not for redistribution. The definitive version was published in ACM Transactions on Computer-Human Interaction (TOCHI), {VOL 20, ISS 5,
Macredie, Robert D., Martin, J, Borsci, S, Young, Terry, Young, T, Martin, Jennifer L., Macredie, RD, Barnett, J, Barnett, Julie, Kuljis, J, Borsci, Simone, Kuljis, Jasna   +11 more
core   +1 more source

Tailored information on alternative fuels: Segmenting future consumers' preferences for information and communication related to alternative fuels

Fuel Communications
Increasing emissions in the mobility sector pose a significant challenge for modern society, contributing extensively to climate change. One promising approach to mitigating these emissions is the development of CO₂-based alternative fuels, which can ...
Julia Offermann, Linda Engelmann, Martina Ziefle   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Enhancement of human computer interaction with facial electromygraphic sensors

, 2009
In this paper we describe a way to enhance human computer interaction using facial Electromyographic (EMG) sensors. Indeed, to know the emotional state of the user enables adaptable interaction specific to the mood of the user.
Stevens, Catherine J. (R8645), Martin Pruzinec, Schultz, Tanja, Guillaume Gibert, Catherine Stevens, Gibert, Guillaume (R14173), Tanja Schultz, Pruzinec, Martin   +7 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Human-computer interaction and security

, 2022
8 S.Historically, computer security has its roots in the military domain with its hierarchical structures and clear and normative rules that are expected to be obeyed (Adams & Sasse, 1999).
Richter, K., Roth, V.
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Personalized Visualization of the Gestures of Parkinson’s Disease Patients with Virtual Reality

Future Internet
Parkinson’s disease is a neurological disorder characterized by motor and non-motor symptoms. Assessment methods, despite the many years of existence of the disease, lack individualized visualization. On the other hand, virtual reality promises immersion
Konstantinos Sakkas, Eirini Georgia Dimitriou, Niki Eleni Ntagka, Nikolaos Giannakeas, Konstantinos Kalafatakis, Alexandros T. Tzallas, Evripidis Glavas   +6 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source