Results 121 to 130 of about 720,543 (314)

Proceedings of the 1st International Conference on Advances in Computer-Human Interaction, ACHI 2008: Preface

, 2008
10.1109/ACHI.2008.4Proceedings of the 1st International Conference on Advances in Computer-Human Interaction, ACHI 2008x ...
Oinas-Kukkonen, H., Dascalu, Sergiu, Latombe, J.-C., Lovell, Brian C., Ge, Shuzhi Sam, Nearchou, Andreas C., Viniotis, Yannis, Wang, A.I., Dragan, I.C., Milani, A., Oinas-Kukkonen, Harri, Oinas Kukkonen, Harri, Viniotis, Y., Lovell, B.C., Nearchou, A.C., Latombe, Jean-Claude, Zaytoon, Janan, Ge, S.S., Wang, Alf Inge, Latombe, Jean Claude, Milani, Alfredo, Nakashima, T., Nakashima, Tomoharu, Dragan, Irinel C., Dascalu, S., Zaytoon, J.   +25 more
core   +1 more source

The Interactive Urban Robot: User-centered development and final field trial of a direction requesting robot

Paladyn, 2015
In this article, we present the user-centered development of the service robot IURO. IURO’s goal is to find the way to a designated place in town without any previous map knowledge, just by retrieving information from asking pedestrians for directions ...
Weiss Astrid, Mirnig Nicole, Bruckenberger Ulrike, Strasser Ewald, Tscheligi Manfred, Kühnlenz (Gonsior) Barbara, Wollherr Dirk, Stanczyk Bartlomiej   +7 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Enhancement of human computer interaction with facial electromygraphic sensors

, 2009
In this paper we describe a way to enhance human computer interaction using facial Electromyographic (EMG) sensors. Indeed, to know the emotional state of the user enables adaptable interaction specific to the mood of the user.
Stevens, Catherine J. (R8645), Martin Pruzinec, Schultz, Tanja, Guillaume Gibert, Catherine Stevens, Gibert, Guillaume (R14173), Tanja Schultz, Pruzinec, Martin   +7 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Concept-Driven Interaction Design Research

, 2010
In this article, we explore a concept-driven approach to interaction design research with a specific focus on theoretical advancements. We introduce this approach as a complementary approach to more traditional, and well-known, user-centered interaction ...
Mikael Wiberg, Wiberg, Mikael,, Stolterman, Erik,, Erik Stolterman   +3 more
core   +1 more source

Understanding glyph characteristics on the legibility for native and non-native speakers in virtual reality

Frontiers in Virtual Reality
IntroductionMultilingual communication shapes education, culture, and decision-making, However, we lack a clear picture of how native writing systems influence visual processing.MethodsWe conducted virtual reality experiments comparing native Chinese ...
Huidan Zhang, Daisuke Sakamoto, Tetsuo Ono   +2 more
doaj   +1 more source

Saliency in human-computer interaction [PDF]

, 2006
This paper considers ways in which a person can cue and constrain an artificial agent's attention to salient features. In one experiment, a person uses gestures to direct an otherwise autonomous robot hand through a known task. Each gesture instantiates the key spatial and intentional features for the task at that moment in time.
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source